Nokea
A nurse in the post-anesthesia recovery unit is caring for a client who received a nondepolarizing neuromuscular blocking agent and has muscle weakness. The nurse should anticipate a prescription for which of the following medications?
- A. Neostigmine
- B. Naloxone
- C. Dantrolene
- D. Vecuronium
Correct Answer: A
Rationale: Neostigmine reverses nondepolarizing neuromuscular blockers by increasing acetylcholine.
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You are evaluating the discharge teaching you have done with your patient concerning their drug therapy. What statement from the patient would indicate that teaching had been effective?
- A. I have to take three pills each day. It doesn't matter when.'
- B. I should take the white pill in the morning and the green pill in the afternoon. I don't know what they are called.'
- C. I need to tell all my other doctors that I am taking this Coumadin because it could interact with other drugs.'
- D. I think I could cut that pill in half if I wanted to.'
Correct Answer: C
Rationale: Understanding drug interactions with Coumadin (warfarin) shows effective teaching on safety and coordination of care.
Which of the following diagnostic studies would NOT indicate a problem related to a reductase inhibitor?
- A. Elevated serum transaminase
- B. Increased serum creatinine
- C. Elevated creatinine kinase
- D. Increased white blood cell counts
Correct Answer: D
Rationale: WBC elevation is unrelated to reductase inhibitors; others indicate liver, kidney, or muscle issues.
Why is diclofenac combined with misoprostol?
- A. They are synergistic
- B. They are additive
- C. To reduce hepatic side effects
- D. To prevent diclofenac-related gastric ulcers
Correct Answer: D
Rationale: Misoprostol protects against diclofenac-induced gastric ulcers.
A non-competitive antagonist :
- A. Alters the mechanism of action of an agonist
- B. Alters the potency of an agonist
- C. Shifts the dose-response curve of an agonist to the right
- D. Decreases the maximum response to an agonist
Correct Answer: D
Rationale: Non-competitive antagonists reduce the maximal response (efficacy), not potency, distinguishing them from competitive antagonists.
In clinical practice glucocorticoids are used for:
- A. Cavernosus tuberculosis
- B. Syphilis
- C. Fungal disease
- D. Colagenosis (Systemic connective tissue disorders, e.g. rheumatism, systemic lupus erythematosus, etc.)
Correct Answer: D
Rationale: Glucocorticoids are used for collagenoses like lupus due to their anti-inflammatory and immunosuppressive effects.