Nokea
A nurse is assessing a client who is taking Amiodarone to treat Atrial Fibrillation. Which of the following findings is a manifestation of Amiodarone toxicity?
- A. Light yellow urine
- B. Report of tinnitus
- C. Productive cough
- D. Blue-gray skin discoloration
Correct Answer: C
Rationale: Productive cough may indicate pulmonary toxicity, a serious amiodarone side effect.
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Which phenothiazine has the least extra pyramidal effect
- A. Thioridazine
- B. Chlorpromazine
- C. Triflupromazine
- D. Fluphenazine
Correct Answer: A
Rationale: Thioridazine has fewer extrapyramidal effects.
Before administering a prescription medication, what information does the nurse find on the drug label? (Select all that apply.)
- A. Brand name
- B. Generic name
- C. Drug concentration
- D. Adverse effects
Correct Answer: D
Rationale: Prescription drug labels will contain the brand name, generic name, drug concentration, and expiration date. Adverse effects will not be listed on drug labels.
What needs to happen to the protein-drug complex for the drugs to reach the cells where the drug can act?
- A. The protein-drug complex must break itself into smaller pieces to enter the capillaries.
- B. The binding site on the protein picks up a chemical to make it soluble in the serum.
- C. The drug must break away from the protein-binding site and float freely.
- D. The drug must be dissolved in the plasma so it can enter the capillaries and then the tissues.
Correct Answer: C
Rationale: Most drugs are bound, to some extent, to proteins in the blood to be carried into circulation. The protein-drug complex is relatively large and cannot enter into capillaries and then into tissues to react. The drug must be freed from the protein's binding site at the tissues. This occurs without the introduction of another chemical or by dissolving in it plasma.
A nurse has received an order to administer two drugs at the same time of the day. The nurse should first:
- A. Wash her hands before handling the medications
- B. Consult a drug guide for compatibility
- C. Question the patient concerning drug allergies
- D. Identify the patient by checking the armband and asking the patient to state his or her name
Correct Answer: B
Rationale: Consulting a drug guide for compatibility is critical to avoid adverse interactions when administering two drugs simultaneously. Hand washing, allergy checks, and patient identification are also essential but follow ensuring drug compatibility to prevent harm.
All of the following are protein bound except:
- A. Propranolol
- B. Atenolol
- C. Phenylbutazone
- D. Warfarin
Correct Answer: B
Rationale: Atenolol has low protein binding; others bind extensively.