A nurse is caring for a client receiving norethindrone for endometriosis. After administering the drug, the nurse would assess the client for which of the following? Select all that apply.
- A. Breast tenderness
- B. Edema
- C. Somnolence
- D. Hyperglycemia
- E. Thinning hair
Correct Answer: A,B
Rationale: Adverse reactions associated with norethindrone, a progestin, include breast tenderness, edema, insomnia, breakthrough bleeding, weight changes, and acne. Hyperglycemia and thinning hair are not associated with norethindrone.
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A nurse's preadministration assessment for a client about the receive oxymetholone (Anadrol-50) should include which of the following? Select all that apply.
- A. Weight
- B. Blood glucose
- C. Serum lipid levels
- D. Hepatic function tests
- E. Pain assessment
Correct Answer: A,C,D
Rationale: A nurse's preadministration assessment for a client about the receive oxymetholone (Anadrol-50) should include weight, blood pressure, pulse, respiratory rate, complete blood count, hepatic function tests, serum electrolytes, and serum lipid levels.
A client with delayed puberty has been advised to undertake transdermal androgen therapy, Androderm. Which of the following instructions should the nurse provide the client to help promote an optimal response to this therapy?
- A. Apply the Androderm to the underside of the scrotum.
- B. Repeat the application to the scrotum after 3 days.
- C. Moisten the skin before the application.
- D. Apply immediately after removing the cover.
Correct Answer: D
Rationale: Applying the system immediately after opening the pouch and removing the protective cover may help obtain an optimal response to the transdermal androgen delivery system. The drug should not be applied to the underside of the scrotum. It is applied to clean, dry skin on the abdomen, thigh, back, or upper arm. Thus, the skin should not be moistened before the application; rather, it should be dry. Seven days should be allowed between applications to a specific site, and application to the same site should not be repeated after 3 days.
A female client receiving fluoxymesterone for metastatic breast cancer is disturbed by the physical changes seen in her body. The nurse provides support to the client based on assessment of which of the following features the client is experiencing related to this therapy?
- A. Deepening of the voice
- B. Hypopigmentation of the skin
- C. Decrease in clitoris size
- D. Increase in body weight
Correct Answer: A
Rationale: Deepening of the voice may be seen as a feature of virilization following male hormone therapy in a female client. Virilization is the acquisition of male characteristics in the female. Other features of virilization include pigmentation, and not hypopigmentation, of the skin and an increase, not a decrease, in the size of the clitoris. An increase in body weight is not a sign of virilization. It may occur due to impaired nutrition of the body.
A nurse is describing the action of estrogen in the female body to a client. Which of the following would the nurse include? Select all that apply.
- A. Diuresis
- B. Calcium and phosphorus conservation
- C. Thinning of the cervical mucus
- D. Protein catabolism
- E. Stimulation of fallopian tube contraction
Correct Answer: B,C,E
Rationale: The actions of estrogen on the female body include fluid retention, calcium and phosphorus conservation, protein anabolism, thinning of the cervical mucus, stimulation of fallopian tube contraction, growth of axillary and pubic hair, restoration of the endometrium after menstruation, and at puberty promotion of growth and development of the vagina, uterus, fallopian tubes, and breasts.
A female client with inoperable advanced breast cancer is prescribed methyltestosterone. The nurse would be alert for the development of which of the following? Select all that apply.
- A. Amenorrhea
- B. Acne
- C. Facial hair growth
- D. Somnolence
- E. Mania
Correct Answer: A,B,C
Rationale: A nurse should advise a female client beginning therapy with methyltestosterone (Testred) for the treatment of inoperable advanced breast carcinoma of the following adverse reactions: amenorrhea, other menstrual irregularities, acne, male-pattern baldness, and virilization (facial hair growth, voice deepening, and clitoromegaly).
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