Nokea
A nurse is caring for a client who has increased intracranial pressure and is receiving Mannitol. Which of the following findings should the nurse report to the provider?
- A. Blood glucose 150 mg/dL
- B. Urine output 40 mL/hr
- C. Dyspnea
- D. Bilateral equal pupil size
Correct Answer: C
Rationale: Dyspnea may indicate pulmonary edema, a potential complication of mannitol therapy.
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Pharmacokinetics is:
- A. The study of biological and therapeutic effects of drugs
- B. The study of absorption, distribution, metabolism and excretion of drugs
- C. The study of mechanism of drugs
- D. The study of methods of new drug development
Correct Answer: B
Rationale: Pharmacokinetics focuses on how the body handles a drug, including absorption, distribution, metabolism, and excretion (ADME), distinguishing it from pharmacodynamics, which studies drug effects.
When administering an intradermal injection, the nurse would use a 1-mL syringe with which gauge of needle? Select one that does not apply.
- A. 26 gauge
- B. 27 gauge
- C. 29 gauge
- D. 25 gauge
Correct Answer: C
Rationale: A 1-mL syringe with a 25- to 27-gauge needle that is 1/4 to 5/8 inches long is best suited for intradermal injections.
The U.S. Drug Enforcement Administration:
- A. Registers manufacturers and prescribers of controlled substances
- B. Regulates NP prescribing at the state level
- C. Sanctions providers who prescribe drugs off-label
- D. Provides prescribers with a number they can use for insurance billing
Correct Answer: A
Rationale: The DEA registers those handling controlled substances , not state NP rules , off-label sanctions , or insurance numbers .
Carbamazepine has a Black Box Warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to:
- A. Decreased effectiveness of carbamazepine in treating seizures in Asian patients with HLA-B*1502 allele
- B. Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele
- C. Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele
- D. Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine
Correct Answer: C
Rationale: HLA-B*1502 in Asians increases Stevens-Johnson syndrome risk with carbamazepine , per FDA warning, not efficacy or interactions .
All increase dopaminergic transmission except
- A. Bromocriptine
- B. Metoclopramide
- C. Chlorpromazine
- D. Reserpine
Correct Answer: B
Rationale: Metoclopramide blocks dopamine receptors; others affect dopamine differently.