Nokea
A nurse is preparing a teaching plan for a client who is prescribed an oral medication. As part of the plan, the nurse expects to describe the importance of absorption. The nurse would integrate knowledge of which of the following as a mechanism for absorption in the gastrointestinal tract? Select one that does not apply.
- A. Active transport
- B. Transposition
- C. Passive transport
- D. Pinocytosis
Correct Answer: B
Rationale: During absorption, the drug particles in the GI tract are moved into the body fluids via active transport, passive transport, and pinocytosis.
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A patient is being seen in the clinic for rheumatoid arthritis. Which of the following statements would indicate that she may be developing a complication from her rheumatoid medication, chloroquine (Aralen)?
- A. I have to urinate all the time.'
- B. Sometimes I have blurred vision.'
- C. I have tingling and numbness in my arms and legs.'
- D. Sometimes I feel like I am losing my balance when I walk.'
Correct Answer: B
Rationale: Chloroquine (Aralen) can cause ocular toxicity with blurring of vision, color vision changes, corneal damage, and blindness. Increased urination and tingling and numbness are signs of hyperkalemia and hypokalemia. Loss of balance can be caused by auditory damage due to drug toxicity.
A client with Crohn's disease is scheduled to receive an infusion of infliximab (Remicade). The nurse assisting in caring for the client should take which action to monitor the effectiveness of treatment?
- A. Monitoring the leukocyte count for 2 days after the infusion
- B. Checking the frequency and consistency of bowel movements
- C. Checking serum liver enzyme levels before and after the infusion
- D. Carrying out a Hematest on gastric fluids after the infusion is completed
Correct Answer: B
Rationale: The principal manifestations of Crohn's disease are diarrhea and abdominal pain. Infliximab (Remicade) is an immunomodulator that reduces the degree of inflammation in the colon, thereby reducing the diarrhea. Options 1, 3, and 4 are unrelated to this medication.
A patient who is taking isoniazid (INH) as part of a two-drug tuberculosis treatment regimen reports tingling of the fingers and toes. The nurse will recommend discussing which treatment with the provider?
- A. Adding pyrazinamide
- B. Changing to ethambutol
- C. Increasing oral fluid intake
- D. Taking pyridoxine (B6)
Correct Answer: D
Rationale: Pyridoxine prevents INH-induced neuropathy (tingling); changing drugs or fluids doesn't address this. Peripheral neuropathy is an adverse reaction to INH, so pyridoxine is usually given to prevent this.
Which of the following has a strong anti-inflammatory effect:
- A. Prednisolone
- B. Triamcinolone
- C. Dexamethasone
- D. Prednisone
Correct Answer: C
Rationale: Dexamethasone has a strong anti-inflammatory effect due to its high glucocorticoid potency.
Newborns are at risk for early vitamin K deficiency bleeding and the American Academy of Pediatrics recommends that all newborns receive:
- A. IM vitamin K (phytonadione) within 24 hours of birth
- B. Oral vitamin K supplementation in the first 3 weeks of life
- C. Formula containing vitamin K or breast milk
- D. Oral vitamin K in the first 24 hours after birth
Correct Answer: A
Rationale: IM vitamin K is standard to prevent vitamin K deficiency bleeding in newborns.