A nurse is preparing to administer a prescribed drug. Which information about the drug would be most important for the nurse to know?
- A. Normal dosage range
- B. Special precautions in administration
- C. Drug's most common adverse effects
- D. All the above
Correct Answer: D
Rationale: The nurse must have factual knowledge of each drug given, the reason for use of the drug, the drug's general action, the more common adverse reactions associated with the drug, special precautions in administration (if any), and the normal dose ranges.
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A nurse in a clinic is caring for a group of clients. The nurse should contact the provider about a potential contraindication to a medication for which of the following clients?
- A. A client at 8 weeks of gestation who asks for an influenza immunization
- B. A client who takes Prednisolone and has a no fungal infection
- C. A client who has chronic liver disease and is taking hydrocortone
- D. A client who has Peptic Ulcer Disease, takes Sucralfate, and tells the nurse she has started taking OTC Aluminum Hydroxide
Correct Answer: C
Rationale: Prednisolone worsens fungal infections, hydrocortisone is risky in liver disease, and warfarin with pregnancy increases bleeding risk.
Ototoxicity is more likely if aminoglycosides are administered with which of the following drug classes?
- A. Loop diuretics
- B. Metformin
- C. Vancomycin
- D. Cephalosporins
Correct Answer: A
Rationale: Loop diuretics (e.g., furosemide) enhance aminoglycoside ototoxicity by increasing inner ear damage risk.
Which phenothiazine has the least extra pyramidal effect
- A. Thioridazine
- B. Chlorpromazine
- C. Triflupromazine
- D. Fluphenazine
Correct Answer: A
Rationale: Thioridazine has fewer extrapyramidal effects.
A 57-year-old man was recently diagnosed with Type-2 diabetes mellitus and placed on a medication. He began having myalgias and feeling sick and later developed respiratory distress, so he went to the hospital. His pH was 7.2, and he had elevated blood lactate levels. Which drug is likely causing his problem?
- A. Acarbose
- B. Glyburide
- C. Metformin
- D. Pioglitazone
Correct Answer: C
Rationale: Metformin can cause lactic acidosis, a rare but serious side effect, presenting with low pH and elevated lactate levels.
Methanol causes blindness due to its
- A. Hypersensitivity reactions
- B. Conjugated products
- C. Idiosyncratic reaction
- D. Oxidative products
Correct Answer: D
Rationale: Methanol's metabolite, formic acid (oxidative product), damages the optic nerve, causing blindness.