Nokea
A nurse is teaching a client who has a new prescription for Brimonidine ophthalmic drops and wears soft contact lenses. Which of the following instructions should the nurse include in the teaching?
- A. This medication can stain your contacts.
- B. This medication can cause your pupils to constrict.
- C. This medication can absorb into your contacts.
- D. This medication can slow your heart rate.
Correct Answer: C
Rationale: Brimonidine can absorb into contacts , requiring removal before use to avoid irritation.
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The drug used for the treatment of trachomoniasis is:
- A. Tetracycline
- B. Suramin
- C. Metronidazole
- D. Pyrimethamine
Correct Answer: C
Rationale: Metronidazole is the standard treatment for trichomoniasis, a protozoal infection caused by Trichomonas vaginalis, due to its specific antiprotozoal activity.
Ray has been diagnosed with hypertension and an angiotensin-converting enzyme inhibitor is determined to be needed. Prior to prescribing this drug, the NP should assess for:
- A. Hypokalemia
- B. Impotence
- C. Decreased renal function
- D. Inability to concentrate
Correct Answer: C
Rationale: ACE inhibitors can worsen renal function, necessitating baseline assessment.
NSAIDs combat fever by inhibiting which prostaglandin?
- A. Prostaglandin E2
- B. Prostaglandin I2
- C. Prostaglandin D2
- D. Prostaglandin F2
Correct Answer: A
Rationale: Prostaglandin E2 mediates fever in the hypothalamus; NSAIDs reduce fever by inhibiting its synthesis.
Ultra-rapid metabolizers of drugs may have:
- A. To have dosages of drugs adjusted downward to prevent drug accumulation
- B. Active drug rapidly metabolized into inactive metabolites, leading to potential therapeutic failure
- C. Increased elimination of active, nonmetabolized drug
- D. Slowed metabolism of a prodrug into an active drug, leading to an accumulation of prodrug
Correct Answer: B
Rationale: Ultra-rapid metabolizers (e.g., CYP2D6) quickly inactivate drugs , risking therapeutic failure, requiring higher doses, not lower or slowed metabolism .
A nurse is caring for a client who is receiving daily doses of Oprelvekin. Which of the following laboratory values should the nurse monitor to determine effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood count
Correct Answer: C
Rationale: Oprelvekin increases platelet count , its primary therapeutic effect.