A nurse is teaching a patient about a new prescription for hydrochlorothiazide. Which statement indicates that the patient understands the teaching?
- A. I should increase my potassium intake.
- B. I may experience swelling in my legs.
- C. I need to monitor my blood sugar levels.
- D. I can take this medication any time of the day.
Correct Answer: A
Rationale: Hydrochlorothiazide can cause hypokalemia; increasing potassium intake shows understanding, unlike swelling (opposite effect) or timing flexibility (best in morning).
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The client with metastatic breast cancer is receiving tamoxifen. The nurse specifically monitors which laboratory value while the client is taking this medication?
- A. Glucose level
- B. Calcium level
- C. Potassium level
- D. Prothrombin time
Correct Answer: B
Rationale: Tamoxifen may increase calcium, cholesterol, and triglyceride levels. Before the initiation of therapy, a complete blood count, platelet count, and serum calcium levels should be assessed. These blood levels, along with cholesterol and triglyceride levels, should be monitored periodically during therapy. The nurse should assess for hypercalcemia while the client is taking this medication. Signs of hypercalcemia include increased urine volume, excessive thirst, nausea, vomiting, constipation, hypotonicity of muscles, and deep bone and flank pain.
Angiotensin-converting enzyme inhibitors are the drug of choice in treating hypertension in diabetic patients because they:
- A. Improve insulin sensitivity
- B. Improve renal hemodynamics
- C. Reduce the production of angiotensin II
- D. All of the above
Correct Answer: D
Rationale: ACE inhibitors benefit diabetics by enhancing insulin sensitivity, protecting kidneys, and blocking angiotensin II.
T½ of a drug can determine all the following
- A. Closing interval
- B. Elimination time
- C. Steady Plasma Concentration
- D. Therapeutic dosage
Correct Answer: D
Rationale: Half-life (t½) informs dosing intervals to maintain therapeutic levels.
The direct costs of drug therapy include:
- A. The actual cost of acquiring the medication
- B. The loss of income due to illness
- C. Pain and suffering due to inadequate drug therapy
- D. The cost of a funeral associated with premature death
Correct Answer: A
Rationale: Direct costs are the tangible expenses of acquiring the drug itself.
Nicotinic receptors are seen in
- A. Skeletal muscle
- B. Visceral smooth muscle
- C. Cardiac muscle
- D. Salivary glands
Correct Answer: A
Rationale: Nicotinic receptors are primarily at skeletal muscle neuromuscular junctions.
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