Nokea
A nursing is planning care for a client who is receiving Furosemide IV for peripheral edema. Which of the following interventions should the nurse include in the plan of care? (Select all that apply.)
- A. Assess for tinnitus.
- B. Report urine output 50 mL/hr.
- C. Monitor Calcium levels.
- D. Elevate the head of bed slowly before ambulation.
Correct Answer: A
Rationale: Furosemide can cause tinnitus , hypokalemia , and requires potassium-rich foods like bananas.
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Several processes enable a drug to reach a specific concentration in the body. Together they are called dynamic equilibrium. What are these processes? (Select one that does not apply.)
- A. Distribution to the active site
- B. Biotransformation
- C. Absorption from the muscle
- D. Excretion
Correct Answer: C
Rationale: The actual concentration that a drug reaches in the body results from a dynamic equilibrium involving several processes: Absorption from the site of entry (can be from the muscle, the gastrointestinal (GI) tract if taken orally, of the subcutaneous tissue if given by that route); Distribution to the active site; biotransformation (metabolism) in the liver; excretion from the body. Interaction with other drugs is not part of the dynamic equilibrium.
A nurse is working as a member of a research team involved in exploring the unique response to drugs each individual displays based on genetic make-up. What is this area of study is called?
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a patient's unique genetic make-up. Pharmacotherapeutics is the branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes the costs involved in drug therapy.
A non-competitive antagonist :
- A. Alters the mechanism of action of an agonist
- B. Alters the potency of an agonist
- C. Shifts the dose-response curve of an agonist to the right
- D. Decreases the maximum response to an agonist
Correct Answer: D
Rationale: Non-competitive antagonists reduce the maximal response (efficacy), not potency, distinguishing them from competitive antagonists.
Why is diclofenac combined with misoprostol?
- A. They are synergistic
- B. They are additive
- C. To reduce hepatic side effects
- D. To prevent diclofenac-related gastric ulcers
Correct Answer: D
Rationale: Misoprostol protects against diclofenac-induced gastric ulcers.
Which statement is not correct regarding long acting medications:
- A. Effective for treatment of diabetes mellitus type I
- B. Effective for treatment of diabetes mellitus type II
- C. In for intravenous use
- D. Is for subcutaneous use
Correct Answer: C
Rationale: Long-acting insulins like glargine are administered subcutaneously, not intravenously, for sustained glucose control.