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A patient presents with sudden-onset, painless vision loss in the right eye. Fundoscopic examination reveals a cherry-red spot at the macula and attenuated retinal vessels. Which of the following conditions is most likely responsible for this presentation?

  • A. Central retinal artery occlusion
  • B. Central retinal vein occlusion
  • C. Retinal detachment
  • D. Acute angle-closure glaucoma
Correct Answer: A

Rationale: The presentation described with sudden-onset, painless vision loss, a cherry-red spot at the macula, and attenuated retinal vessels is classic for central retinal artery occlusion (CRAO). CRAO occurs when the central retinal artery, which supplies blood to the inner retinal layers, becomes occluded. The cherry-red spot is due to the exposure of the underlying choroid, which still appears red as it is not affected by the blockage. Attenuated retinal vessels and a pale retina may also be seen due to ischemia. In contrast, central retinal vein occlusion (choice B) presents with sudden painless vision loss, retinal hemorrhages, dilated retinal veins, and cotton-wool spots. Retinal detachment (choice C) typically presents with flashes, floaters, and a curtain-like shadow across the vision. Acute angle-closure glaucoma (