ATI Capstone Pharmacology Assessment Related

Review ATI Capstone Pharmacology Assessment related questions and content

A patient requires a nonopioid medication. The nurse knows that which medication will cause the least gastrointestinal distress?

  • A. Aspirin
  • B. Ketorolac
  • C. Celecoxib
  • D. Ibuprofen
Correct Answer: C

Rationale: Celecoxib is a selective COX-2 inhibitor, which means it primarily targets the COX-2 enzyme involved in inflammation and pain while sparing the COX-1 enzyme that protects the stomach lining. This selectivity reduces the risk of gastrointestinal distress, such as ulcers and bleeding, compared to non-selective NSAIDs like aspirin, ketorolac, and ibuprofen. Therefore, celecoxib is the best choice for patients who require a nonopioid medication with minimal gastrointestinal side effects. Nurses should consider this when selecting pain management options for patients with a history of gastrointestinal issues.