Nokea
A patient with gout has been treated with allopurinol for 2 months. The nurse will monitor laboratory results for which therapeutic effect?
- A. Decreased uric acid levels
- B. Decreased prothrombin time
- C. Decreased white blood cell count
- D. Increased hemoglobin and hematocrit levels
Correct Answer: A
Rationale: Treatment of gout with allopurinol should result in decreased uric acid levels.
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During assessment of a patient with osteoarthritis pain, the nurse knows that which condition is a contraindication to the use of nonsteroidal anti-inflammatory drugs (NSAIDs)?
- A. Renal disease
- B. Diabetes mellitus
- C. Headaches
- D. Rheumatoid arthritis
Correct Answer: A
Rationale: Contraindications to NSAIDs include known drug allergy and conditions that place a patient at risk for bleeding, such as vitamin K deficiency, and peptic ulcer disease. Patients with documented aspirin allergy must not receive NSAIDs. Other common contraindications are those that apply to most drugs, including severe renal or hepatic disease.
A patient calls the clinic to ask about taking a glucosamine-chondroitin supplement for arthritis. The nurse reviews the medication history and notes that there will be a concern for drug interactions if the patient is also taking medications for which disorder?
- A. Type 2 diabetes mellitus
- B. Hypothyroidism
- C. Hypertension
- D. Angina
Correct Answer: A
Rationale: Glucosamine may reduce the effectiveness of antidiabetic drugs by worsening insulin resistance, necessitating closer monitoring of blood glucose levels in patients with type 2 diabetes mellitus.
A patient is taking the nonsteroidal anti-inflammatory drug indomethacin (Indocin) as treatment for pericarditis. The nurse will teach the patient to watch for which adverse effect?
- A. Tachycardia
- B. Nervousness
- C. Nausea and vomiting
- D. Dizziness
Correct Answer: C
Rationale: Gastrointestinal effects include dyspepsia, heartburn, epigastric distress, nausea, vomiting, anorexia, abdominal pain, and others.
A mother brings her toddler into the emergency department and tells the nurse that she thinks the toddler has eaten an entire bottle of chewable aspirin tablets. The nurse will assess for which most common signs of salicylate intoxication in children?
- A. Photosensitivity and nervousness
- B. Tinnitus and hearing loss
- C. Acute gastrointestinal bleeding
- D. Hyperventilation and drowsiness
Correct Answer: D
Rationale: The most common manifestations of chronic salicylate intoxication in children are hyperventilation and CNS effects, such as dizziness, drowsiness, and behavioral changes.
The nurse is reviewing the therapeutic effects of nonsteroidal anti-inflammatory drugs (NSAIDs), which include which effect?
- A. Anxiolytic
- B. Sedative
- C. Antipyretic
- D. Antimicrobial
Correct Answer: C
Rationale: NSAIDs have antipyretic effects but not the other effects listed.