Genitourinary System Assessment Related

Review Genitourinary System Assessment related questions and content

A patient with severe infectious disease is being treated with aminoglycoside * antibiotics. Which of the following diuretic should be avoided for this patient because of the serious side effect shared by both drugs?

  • A. Furosemide
  • B. Hydrochlorothiazide
  • C. Spironolactone
  • D. Acetazolamide
Correct Answer: A

Rationale: The correct answer is A: Furosemide. Aminoglycoside antibiotics can cause ototoxicity and nephrotoxicity. Furosemide, a loop diuretic, also has the potential to cause ototoxicity and nephrotoxicity, leading to a serious side effect when combined with aminoglycosides. On the other hand, choices B, C, and D (Hydrochlorothiazide, Spironolactone, and Acetazolamide) do not share the same serious side effects with aminoglycosides. Hydrochlorothiazide is a thiazide diuretic that acts on the distal convoluted tubule, Spironolactone is a potassium-sparing diuretic that acts on the collecting duct, and Acetazolamide is a carbonic anhydrase inhibitor diuretic that works in the proximal tubule. Therefore, Furosemide should