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A provider prescribes phenobarbital for a client who has a seizure disorder. The medication has a long half-life of 4 days. How many times per day should the nurse expect to administer this medication?
- A. One
- B. Two
- C. Three
- D. Four
Correct Answer: A
Rationale: A long half-life of 4 days means the drug remains effective for an extended period, typically requiring once-daily dosing.
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A nurse is assessing a client and notes that the client has developed swelling of the eyelids and lips after administration of a prescribed medication. The nurse interprets this finding as specifically indicating which of the following?
- A. Mild allergic reaction
- B. Anaphylactic shock
- C. Angioedema
- D. Drug idiosyncrasy
Correct Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by the collection of fluid in the subcutaneous tissues, most commonly affecting the eyelids, lips, mouth, and throat. Allergic reactions can be manifested by a wide range of signs and symptoms such as itching, rashes, and hives. Anaphylactic shock is a serious allergic reaction that requires immediate medical attention. Drug idiosyncrasy describes any unusual or abnormal reaction to a drug, one that is different from the one normally expected.
Which of the following is corresponding to the following statement: this drug is used for diabetes mellitus and while using there is an increased risk of pancreatitis:
- A. Miglitol
- B. Pioglitazon
- C. Exenatide
- D. Glimepiride
Correct Answer: C
Rationale: Exenatide, a GLP-1 agonist, treats diabetes and has a known risk of pancreatitis as a rare but serious side effect.
Beta blocker are used in all, except
- A. Variant angina
- B. Mild hypertension
- C. Glaucoma
- D. Thyrotoxicosis
Correct Answer: A
Rationale: Beta-blockers worsen variant angina due to unopposed alpha constriction.
A patient is to receive a daily dose of 240 mg of a medication. The dose is supposed to be divided evenly so that the drug is given every 6 hours. How much of the drug should be given at each dose?
- A. 30 mg
- B. 40 mg
- C. 50 mg
- D. 60 mg
Correct Answer: D
Rationale: Because there are 24 hours in a day, giving a drug every 6 hours would mean giving the drug four times a day. Because the total daily dose is 240 mg, dividing that dose by four would mean each dose should be 60 mg.
Which source contains information specific to nutritional supplements?
- A. USP Dictionary of USAN & International Drug Names
- B. Natural Medicines Comprehensive Database
- C. United States Pharmacopoeia/National Formulary (USP NF)
- D. Drug Interaction Facts
Correct Answer: C
Rationale: United States Pharmacopoeia/National Formulary contains information specific to nutritional supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug names, pronunciation guide, and possible future FDA approved drugs; it does not include nutritional supplements. Natural Medicines Comprehensive Database contains evidence-based information on herbal medicines and herbal combination products; it does not include information specific to nutritional supplements. Drug Interaction Facts contains comprehensive information on drug interaction facts; it does not include nutritional supplements.