Nokea
There is enough preliminary evidence to recommend that children with autism receive which supplemental nutrient?
- A. Vitamin B1 (thiamine)
- B. Vitamin B2 (riboflavin)
- C. Calcium
- D. Omega-3 fatty acids
Correct Answer: D
Rationale: Preliminary evidence suggests omega-3 fatty acids may benefit children with autism.
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Ciprofloxacin increases the toxicity of theophylline by
- A. Inhibiting metabolism
- B. Decreasing excretion
- C. Decrease seizure threshold
- D. Promote absorption
Correct Answer: B
Rationale: Ciprofloxacin reduces theophylline clearance, decreasing excretion.
A nurse on a medical-surgical unit administers a hypnotic medication to an older adult client at 2100 . The next morning, the client is drowsy and wants to sleep instead of eating breakfast. Which of the following factors should the nurse identify as a possible reason for the client's drowsiness?
- A. Reduced cardiac function
- B. First pass effect
- C. Reduced hepatic function
- D. Increased gastric motility
Correct Answer: C
Rationale: Reduced hepatic function in older adults slows metabolism of hypnotics, prolonging drowsiness.
symptomatic and metabolic improvement. Until that time, which of the following might be administered adjunctively to suppress glucocorticoid synthesis?
- A. Cimetidine
- B. Cortisol (massive doses)
- C. Fludrocortisone
- D. Ketoconazole
Correct Answer: D
Rationale: Ketoconazole inhibits glucocorticoid synthesis by blocking adrenal steroidogenesis, useful in Cushing's syndrome management.
While administering a medication that the nurse has researched and found to have limited effectiveness, the patient tells the nurse, I have read all about this drug and it is such a wonder drug. I'm so lucky my doctor prescribed it because I just know it will treat my problem. The nurse suspects this drug will be more effective than usual for this patient because of what effect?
- A. Cumulative effect
- B. First-pass effect
- C. Placebo effect
- D. Cross-tolerance effect
Correct Answer: C
Rationale: A drug is more likely to be effective if the patient thinks it will work than if the patient believes it will not work. This is called the placebo effect. If a drug is taken in successive doses at intervals that are shorter than recommended, or if the body is unable to eliminate a drug properly, the drug can accumulate in the body, leading to toxic levels and adverse effects. This is a cumulative effect. First-pass effect addresses the reduction of available drug when taken orally due to metabolism in the liver before the drug reaches the bloodstream. Cross-tolerance is resistance to drugs within the same class.
Beta-blockers decrease triglyceride levels and increase levels of HDL cholesterol.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Beta-blockers typically increase triglycerides and decrease HDL cholesterol, opposite to the statement.