Nokea
Acetyl salicylate & phenobarbitone are better absorbed from stomach because they are
- A. Weak acids remain non-ionic in gastric pH
- B. Weak acids remain ionic in gastric pH
- C. Strong acids fully ionized in gastric pH
- D. Weak bases which are ionized at gastric pH
Correct Answer: A
Rationale: Weak acids like acetyl salicylate (aspirin) and phenobarbitone remain non-ionic in the acidic pH of the stomach, facilitating their absorption through passive diffusion across the gastric mucosa.
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A physician order is written for a patient to receive 500 mL of normal saline IV over 8 hours. If the IV infusion set delivers 15 drops/mL, how many drops per minute should the patient receive?
- A. 15 drops/min
- B. 20 drops/min
- C. 32 drops/min
- D. 64 drops/min
Correct Answer: A
Rationale: If a patient were to receive 500 mL in 8 hours, dividing 500 by 8 would mean that the patient would receive 62.5 mL in 1 hour, or 60 minutes. Setting up the equation, 15 drops/mL/X = 62.5 mL/60 minutes, and cross-multiplying, the answer will be 15 drops/min.
Which of the following is an II generation sulfonylurea drugs, which are used for the treatment of diabetes mellitus type II:
- A. Chlorpropamide
- B. Tolazamide
- C. Tobutamide
- D. Glipizide
Correct Answer: D
Rationale: Glipizide is a second-generation sulfonylurea, more potent and with fewer side effects than first-generation drugs like chlorpropamide.
Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
- A. Drug Facts and Comparisons
- B. Drug Interaction Facts
- C. Handbook on Injectable Drugs
- D. Martindale-The Complete Drug Reference
Correct Answer: A
Rationale: Drug Facts and Comparisons contains drug monographs that describe all drugs in a therapeutic class. Monographs are formatted as tables to allow comparison of similar products, brand names, manufacturers, cost indices, and available dosage forms.
Which of the following is the longest acting newer antihistamine:
- A. Mequitazine
- B. Loratidine
- C. Astemizole
- D. Terfenadine
Correct Answer: C
Rationale: Astemizole has the longest duration among listed antihistamines.
A nurse is teaching a client about the use of Fluticasone to treat Perennial Rhinitis. Which of the following statements by the client indicates an understanding of the teaching?
- A. I should use the spray every 4 hours while I am awake.
- B. It can take as long as 3 weeks before the medication takes a maximum effect.
- C. This medication can also be used to treat motion sickness.
- D. I can use this medication when my nasal passages are blocked.
Correct Answer: B
Rationale: Fluticasone takes up to 3 weeks for full effect , a key point for managing expectations.