Nokea
Donald has been diagnosed with hyperlipidemia. Based on his lipid profile, atorvastatin is prescribed. Rhabdomyolysis is a rare but serious adverse response to this drug. Donald should be told to:
- A. Become a vegetarian because this disorder is associated with eating red meat.
- B. Stop taking the drug if abdominal cramps and diarrhea develop.
- C. Report muscle weakness or tenderness and dark urine to his provider immediately.
- D. Expect 'hot flash' sensations during the first 2 weeks of therapy.
Correct Answer: C
Rationale: Muscle symptoms and dark urine indicate rhabdomyolysis, requiring immediate reporting.
You may also like to solve these questions
Elimination after 4 half lives in first order kinetics is
- A. 84%
- B. 93%
- C. 80.50%
- D. 4.75%
Correct Answer: B
Rationale: After 4 half-lives, 93.75% (1 - 1/16) of the drug is eliminated in first-order kinetics.
Drugs mostly cross biological membranes by
- A. Passive diffusion
- B. Active diffusion
- C. Active transport
- D. Carrier mediated transport
Correct Answer: A
Rationale: Most drugs cross membranes via passive diffusion based on concentration gradients.
A nurse is caring for a child on the pediatric unit. A drug is ordered for the child, but there is no pediatric dose listed for the drug. To make sure that the right dose has been ordered, what will the nurse use to calculate the correct dose?
- A. Surface area
- B. Height
- C. Birth date
- D. Age at gestation
Correct Answer: A
Rationale: Surface area, calculated via nomograms using height and weight, is the most accurate method for pediatric dosing adjustments.
A physician order is written for a patient to receive 500 mL of normal saline IV over 8 hours. If the IV infusion set delivers 15 drops/mL, how many drops per minute should the patient receive?
- A. 15 drops/min
- B. 20 drops/min
- C. 32 drops/min
- D. 64 drops/min
Correct Answer: A
Rationale: If a patient were to receive 500 mL in 8 hours, dividing 500 by 8 would mean that the patient would receive 62.5 mL in 1 hour, or 60 minutes. Setting up the equation, 15 drops/mL/X = 62.5 mL/60 minutes, and cross-multiplying, the answer will be 15 drops/min.
The patient is taking a drug that affects the body by increasing cellular activity. Where does this drug work on the cell?
- A. Receptor sites
- B. Cell membrane
- C. Golgi body
- D. Endoplasmic reticulum
Correct Answer: A
Rationale: Many drugs are thought to act at specific areas on cell membranes called receptor sites. After the receptor site is activated, this in turn activates the enzyme systems to produce certain effects, such as increased or decreased cellular activity, changes in cell membrane permeability, or alterations in cellular metabolism. Receptor sites are generally located on the outside of cells and allow the drug to bypass the cell membrane. The Golgi body and endoplasmic reticulum are not involved in this process.