Nokea
Adherence is improved when a drug can be given once daily. Which of the following drugs can be given once daily?
- A. Tacrine
- B. Donepezil
- C. Memantine
- D. Pyridostigmine
Correct Answer: B
Rationale: Donepezil's long half-life allows once-daily dosing, improving adherence.
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Aminoglycosides are poorly absorbed from the gut and must therefore be delivered via parenteral routes.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Aminoglycosides have poor oral bioavailability due to their polar nature, requiring parenteral administration (e.g., IV or IM) for systemic effects.
Who defines the standards of care for the practice of nursing? (Select one that does not apply.)
- A. State boards of nursing
- B. Hospital policy and procedures
- C. Federal laws regulating health care facilities
- D. The Joint Commission
Correct Answer: B
Rationale: Standards of care are defined by state boards of nursing, federal laws regulating health care facilities, The Joint Commission, and professional nursing associations such as the American Nurses Association. Individual hospital policies and procedures incorporate federal and state guidelines into their respective policies and procedures and are often more stringent than state and federal regulations.
Jim presents with complaints of 'heartburn' that is minimally relieved with Tums (calcium carbonate) and is diagnosed with gastroesophageal reflux disease (GERD). An appropriate first-step therapy would be:
- A. Omeprazole (Prilosec) twice a day
- B. Ranitidine (Zantac) twice a day
- C. Famotidine (Pepcid) once a day
- D. Metoclopramide (Reglan) four times a day
Correct Answer: B
Rationale: Ranitidine , an H2 blocker, is a standard first-line GERD treatment; PPIs are next-step, and metoclopramide is for motility.
Mary has a two-tiered prescription benefit plan, which means:
- A. She can receive differing levels of care based on whether she chooses an 'in-plan' provider or not.
- B. She is eligible for the new Medicare Part D 'donut hole' reduction of costs program.
- C. She pays a higher copay for brand-name drugs than for generic drugs.
- D. She must always choose to be treated with generic drugs first.
Correct Answer: C
Rationale: A two-tiered plan typically involves higher copays for brand-name drugs.
A drug may be classified by which of the following? Select one that does not apply.
- A. The chemical type of the drug's active ingredient
- B. The way the drug is seen
- C. The generic name of the drug
- D. The trade name of the drug
Correct Answer: A
Rationale: A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Generic, trade, and nonproprietary refer to how a drug is named.