Nokea
After administering a medication, for what would the nurse assess the patient?
- A. Drug effects
- B. Allergies
- C. Pregnancy
- D. Preexisting conditions
Correct Answer: A
Rationale: After the medication is administered, the nurse assesses the patient for drug effects, both therapeutic and adverse. The nurse would assess the patient for allergies, preexisting conditions, and pregnancy before administering a medication.
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Probiotics are recommended to be co-administered when are prescribed:
- A. Antacids
- B. Antihypertensives
- C. Antidiarrheals
- D. Antibiotics
Correct Answer: D
Rationale: Probiotics help restore gut flora disrupted by antibiotics.
The patient tells the nurse about a new drug being tested to treat the disease she was diagnosed with and asks the nurse whether the doctor can prescribe a medication still in the preclinical phase of testing. What is the nurses best response?
- A. The doctor would have to complete a great deal of paperwork to get approval to prescribe that drug.
- B. Sometimes pharmaceutical companies are looking for volunteers to test a new drug and the doctor could give them your name.
- C. Drugs in the preclinical phase of testing are only tested on animals and so would not be available to you.
- D. Drugs in the preclinical phase of testing are given only to healthy young men and so would not be available to you.
Correct Answer: C
Rationale: During the preclinical phase of testing drugs are tested on animals and are not available to patients. In phase I, the drug is tested on volunteers who are usually healthy young men. It is only in phase III studies that the drug is made available to prescribers who agree to closely monitor patients getting the medication.
The nurse uses what term to describe the drug level required to have a therapeutic effect?
- A. Critical concentration
- B. Dynamic equilibrium
- C. Selective toxicity
- D. Active transport
Correct Answer: A
Rationale: A critical concentration of a drug must be present before a reaction occurs within the cells to bring about the desired therapeutic effect. A dynamic equilibrium is obtained from absorption of a drug from the site of drug entry, distribution to the active site, metabolism in the liver, and excretion from the body to have a critical concentration. Selective toxicity is the ability of a drug to attach only to those systems found in foreign cells. Active transport is the process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney.
Rho immune globulin (RhoGAM) is given to:
- A. Infants born to women who are Rh positive
- B. Sexual partners of Rh-positive women
- C. Rh-negative women after a birth, miscarriage, or abortion
- D. Rh-negative women at 36 weeks gestation
Correct Answer: C
Rationale: RhoGAM prevents Rh sensitization in Rh-negative women post-delivery; it's not for infants , partners , or late gestation alone.
The major mechanism of gemfibrozil is:
- A. Increased expression of high-affinity LDL receptors
- B. Inhibition of secretion of VLDL by the liver
- C. Reduction of secretion of HDL by the liver
- D. Increased lipid hydrolysis by lipoprotein lipase
Correct Answer: D
Rationale: Gemfibrozil activates lipoprotein lipase, enhancing triglyceride hydrolysis.