Kirk sprained his ankle and is asking for pain medication for his mild-to-moderate pain. The appropriate first-line medication would be:
- A. Ibuprofen (Advil)
- B. Acetaminophen with hydrocodone (Vicodin)
- C. Oxycodone (Oxycontin)
- D. Oral morphine (Roxanol)
Correct Answer: A
Rationale: Ibuprofen is first-line for mild-to-moderate pain due to efficacy and safety.
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When assessing a patient before starting a drug regimen, why would the nurse consider it important to assess baseline kidney function?
- A. To anticipate adverse effects of drugs
- B. To determine patient's baseline electrolyte levels
- C. To determine patient's ability to excrete the drug
- D. To determine patient's ability to metabolize the drug
Correct Answer: C
Rationale: Kidney function determines drug excretion, critical for dosing and avoiding toxicity.
Beta blockers are prescribed for diabetics with caution because of their ability to produce hypoglycemia and block the common symptoms of it. Which of the following symptoms of hypoglycemia is not blocked by these drugs and so can be used to warn diabetics of possible decreased blood glucose?
- A. Dizziness
- B. Increased heart rate
- C. Nervousness and shakiness
- D. Diaphoresis
Correct Answer: D
Rationale: Diaphoresis (sweating) is not blocked by beta blockers and signals hypoglycemia.
The pharmacology students are learning about antibiotics that are known to cause photosensitivity in some patients. What nursing measures would ensure the comfort of patients taking these antibiotics and hopefully avoid serious adverse effects?
- A. Avoiding the use of aspirin and other over-the-counter pain products
- B. Getting a wig or other head cover to avoid heat loss
- C. Avoiding exposure to sunlight or use of a sunscreen and protective clothing if exposure is inevitable
- D. Providing frequent rest periods in a dark room
Correct Answer: C
Rationale: Photosensitivity from antibiotics increases sunburn risk; avoiding sunlight or using protection prevents serious skin reactions.
The nurse uses what term to describe the drug level required to have a therapeutic effect?
- A. Critical concentration
- B. Dynamic equilibrium
- C. Selective toxicity
- D. Active transport
Correct Answer: A
Rationale: A critical concentration of a drug must be present before a reaction occurs within the cells to bring about the desired therapeutic effect. A dynamic equilibrium is obtained from absorption of a drug from the site of drug entry, distribution to the active site, metabolism in the liver, and excretion from the body to have a critical concentration. Selective toxicity is the ability of a drug to attach only to those systems found in foreign cells. Active transport is the process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney.
The following class of drugs may be used to treat Parkinsonian syndrome arising from the use of phenothiazines:
- A. Nicotinic receptor antagonists
- B. Muscarinic receptor antagonists
- C. Adrenoceptor antagonists
- D. Anticholinesterases
Correct Answer: B
Rationale: Antimuscarinics (e.g., benztropine) relieve parkinsonism from phenothiazines.