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Which online drug reference makes available to healthcare providers and the public a standard, comprehensive, up-to-date look up and downloadable resource about medicines?
- A. American Drug Index
- B. American Hospital Formulary
- C. DailyMed
- D. Drug Reference
Correct Answer: C
Rationale: DailyMed makes available to healthcare providers and the public a standard, comprehensive, up-to-date look up and downloadable resource about medicines. The American Drug Index, American Hospital Formulary, and Drug Reference are not designed for public use in this manner.
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Plasma concentration of drug at time 0 is 96(g/ml). If t½ is 2 hours concentration in plasma at 10 hours will be
- A. 48
- B. 24
- C. 12
- D. 3
Correct Answer: D
Rationale: In first-order kinetics, the concentration halves every half-life (t½ = 2 hours). At 10 hours (5 half-lives), 96 → 48 → 24 → 12 → 6 → 3 µg/ml.
Which of the following is the indication for glucocorticoid prescribing?
- A. Cataract
- B. Prevention of respiratory distress
- C. Hypofunction of thyroid gland
- D. Hypocalcemia
Correct Answer: B
Rationale: Glucocorticoids prevent respiratory distress, such as in neonatal respiratory distress syndrome.
A young adult is receiving a maintenance dose of aminophylline, 3 mg/kg PO q6h. The patient weighs 50 kg. How much should the patient receive in a 24-hour period?
- A. 200 mg
- B. 400 mg
- C. 600 mg
- D. 800 mg
Correct Answer: C
Rationale: Use the formula, amount of drug prescribed weight of the patient in kg 4 (q6h in a 24-hour period = 4). 3 50 = 150 mg to be given every 6 hours. To determine how much the patient will receive in a 24-hour period, divide 6 into 24 to equal 4 doses. 4 150 = 600 mg.
Kirk sprained his ankle and is asking for pain medication for his mild-to-moderate pain. The appropriate first-line medication would be:
- A. Ibuprofen (Advil)
- B. Acetaminophen with hydrocodone (Vicodin)
- C. Oxycodone (Oxycontin)
- D. Oral morphine (Roxanol)
Correct Answer: A
Rationale: Ibuprofen is first-line for mild-to-moderate pain due to efficacy and safety.
A nurse is providing information to a client who has a new prescription for Hydrochlorothiazide. Which of the following information should the nurse include?
- A. Take the medication with food.
- B. Plan to take the medication at bedtime.
- C. Expect increased swelling of the ankles.
- D. Fluid intake should be limited in the morning.
Correct Answer: A
Rationale: Taking with food reduces GI upset, a standard instruction for hydrochlorothiazide.