Nokea
When assessing a patient before starting a drug regimen, why would the nurse consider it important to assess baseline kidney function?
- A. To anticipate adverse effects of drugs
- B. To determine patient's baseline electrolyte levels
- C. To determine patient's ability to excrete the drug
- D. To determine patient's ability to metabolize the drug
Correct Answer: C
Rationale: Kidney function determines drug excretion, critical for dosing and avoiding toxicity.
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The major mechanism of gemfibrozil is:
- A. Increased expression of high-affinity LDL receptors
- B. Inhibition of secretion of VLDL by the liver
- C. Reduction of secretion of HDL by the liver
- D. Increased lipid hydrolysis by lipoprotein lipase
Correct Answer: D
Rationale: Gemfibrozil activates lipoprotein lipase, enhancing triglyceride hydrolysis.
Beta-blockers decrease nocturnal melatonin release, thereby contributing to sleep disturbances.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Beta-blockers, especially lipophilic ones, reduce melatonin release, potentially causing sleep disturbances.
The client with acute myelocytic leukemia is being treated with busulfan (Myleran). Which laboratory value would the nurse specifically monitor during treatment with this medication?
- A. Clotting time
- B. Uric acid level
- C. Potassium level
- D. Blood glucose level
Correct Answer: B
Rationale: Busulfan (Myleran) can cause an increase in the uric acid level. Hyperuricemia can produce uric acid nephropathy, renal stones, and acute renal failure. Options 1, 3, and 4 are not specifically related to this medication.
The types of antagonism are:
- A. Summarized
- B. Potentiated
- C. Additive
- D. Competitive
Correct Answer: D
Rationale: Competitive antagonism is a recognized type, involving receptor competition between agonist and antagonist.
Select the first choice drug for acute gout:
- A. Colchicine
- B. Indomethacin
- C. Allopurinol
- D. Dexamethasone
Correct Answer: B
Rationale: Indomethacin, an NSAID, is the first-line treatment for acute gout due to its rapid anti-inflammatory action; colchicine is an alternative, while allopurinol is for prophylaxis.