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After starting treatment for pulmonary tuberculosis a patient complained about red tears and urine. What drug could cause such changes?
- A. Rifampicin
- B. Benzylpenicillin sodium salt
- C. Benzylpenicillin potassium salt
- D. Biseptol-480
Correct Answer: A
Rationale: The correct answer is A: Rifampicin. Rifampicin is known to cause red discoloration of bodily fluids, including tears and urine, due to its side effect of harmless color changes. Benzylpenicillins (B and C) and Biseptol-480 do not typically cause such discoloration. Rifampicin's mechanism of action involves binding to bacterial RNA polymerase, leading to inhibition of RNA synthesis, which is unrelated to the mechanism of the other drugs. Thus, based on the unique side effect profile of Rifampicin and its mechanism of action, it is the most likely drug causing red tears and urine in this scenario.
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The dynamic balance of the species in the normal microflora is known as
- A. dysbiosis
- B. eukaryota
- C. dispersion
- D. eubiosis
Correct Answer: D
Rationale: The correct answer is D: eubiosis. Eubiosis refers to a state of balance and harmony among the species in the normal microflora. This term signifies a healthy and stable microbial community. Dysbiosis (A) is the opposite, indicating an imbalance or disruption in the microflora. Eukaryota (B) refers to organisms with cells containing a nucleus, not specifically related to the balance of microflora. Dispersion (C) refers to the spreading or distribution of microorganisms, not specifically related to their balance. In summary, eubiosis best describes the dynamic balance of species in the normal microflora, making it the correct choice.
Bacteria capable of growing at low temperatures are called:
- A. mesophiles
- B. thermophiles
- C. psychrophiles
- D. halophiles
Correct Answer: C
Rationale: The correct answer is C: psychrophiles. Psychrophiles are bacteria that can grow at low temperatures, typically below 20°C. This is because they have adapted to survive and thrive in cold environments. Mesophiles (A) grow best at moderate temperatures, thermophiles (B) thrive in high temperatures, and halophiles (D) prefer high salt concentrations. Psychrophiles are specifically adapted to cold temperatures, making them the correct choice in this scenario.
Infections of the CNS can be caused by:
- A. Clostridium botulinum
- B. Morbillivirus morbillorum
- C. Clostridium tetani
- D. All are correct
Correct Answer: D
Rationale: The correct answer is D because all three choices, Clostridium botulinum, Morbillivirus morbillorum, and Clostridium tetani, can cause infections of the CNS. Clostridium botulinum can lead to botulism, affecting the nervous system. Morbillivirus morbillorum can cause measles, which can lead to encephalitis. Clostridium tetani can cause tetanus, affecting the central nervous system. Therefore, all three choices can cause infections of the CNS. Choices A, B, and C are incorrect individually because each pathogen can cause CNS infections.
Cholera is a serious gastrointestinal illness caused by bacteria of the genus:
- A. Escherichia
- B. Salmonella
- C. Vibrio
- D. Acinetobacter
Correct Answer: C
Rationale: The correct answer is C: Vibrio. Cholera is caused by Vibrio cholerae bacteria. These bacteria produce a toxin that causes severe diarrhea and dehydration. Escherichia (choice A) and Salmonella (choice B) are known for causing other types of gastrointestinal infections but not cholera. Acinetobacter (choice D) typically causes respiratory infections, not gastrointestinal illnesses like cholera. Therefore, the correct choice is Vibrio as it is specifically associated with cholera.
A man uses dentures. The dentist has noticed mucosal lecions with a white coating in his oral cavity. Microscopy of the coating detected large oval Gram-positive cells. What microorganisms have caused stomatitis in the patient?
- A. Yeast-like fungi of Candida genus
- B. Actinomycetes
- C. Streptococci
- D. Oral spirochetes
Correct Answer: A
Rationale: The correct answer is A: Yeast-like fungi of Candida genus. Candida is a common cause of oral thrush/stomatitis, characterized by mucosal lesions with white coating. The presence of large oval Gram-positive cells is indicative of Candida species. Actinomycetes (B) are filamentous bacteria and not oval Gram-positive cells. Streptococci (C) are spherical bacteria, not oval, and are not commonly associated with stomatitis. Oral spirochetes (D) are spiral-shaped bacteria and not oval Gram-positive cells typically seen in Candida infections. Thus, A is the correct choice based on the characteristic morphology and clinical presentation.