Nokea
All the following cross placenta except
- A. Warfarin
- B. Heparin
- C. Phenindione
- D. Morphine
Correct Answer: B
Rationale: Heparin, a large molecule, does not cross the placenta; others do.
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The nurse, providing patient teaching about home medication use to an older adult, explains that even when drugs are taken properly they can produce negative or unexpected effects. What are these negative or unexpected effects called?
- A. Teratogenic effects
- B. Toxic effects
- C. Adverse effects
- D. Therapeutic effects
Correct Answer: C
Rationale: Negative or unexpected effects are known as adverse or side effects. Teratogenic effects are adverse effects on the fetus and not a likely concern for an older adult. Toxic effects occur when medication is taken in larger than recommended dosages caused by an increase in serum drug levels. Therapeutic effects are the desired actions for which the medication is prescribed.
The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for the client anticipates that which diagnostic study will be prescribed?
- A. Echocardiography
- B. Electrocardiography
- C. Cervical radiography
- D. Pulmonary function studies
Correct Answer: D
Rationale: Bleomycin is an antineoplastic medication (Chemotherapeutic Agents) that can cause interstitial pneumonitis, which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles, which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity occurs. Options 1, 2, and 3 are unrelated to the specific use of this medication.
A nurse is working as a member of a research team involved in exploring the unique response to drugs each individual displays based on genetic make-up. What is this area of study is called?
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a patient's unique genetic make-up. Pharmacotherapeutics is the branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes the costs involved in drug therapy.
When blood glucose levels are difficult to control in type 2 diabetes some form of insulin may be added to the treatment regimen to control blood glucose and limit complication risks. Which of the following statements is accurate based on research?
- A. Premixed insulin analogues are better at lowering HbA1C and have less risk for hypoglycemia
- B. Premixed insulin analogues and the newer premixed insulins are associated with more weight gain than the oral antidiabetic agents
- C. Newer premixed insulins are better at lowering HbA1C and postprandial glucose levels than long-acting insulins
- D. Patients who are not controlled on oral agents and have postprandial hyperglycemia can have neutral protamine Hagedorn insulin added at bedtime
Correct Answer: D
Rationale: NPH at bedtime targets postprandial hyperglycemia in type 2 diabetes; premixed insulins vary in efficacy.
Information technology can be a time-saving device in a busy practice if it is used wisely. One way to make it a help rather than a hindrance is to:
- A. Prioritize what is needed information and spond spending time reading 'interesting' information not central to the problem at hand
- B. Integrate professional and personal searching so that the same browser does not need to be accessed repeatedly
- C. Check e-mail frequently so that patient questions can be addressed promptly
- D. Check for viruses, spyware, and malware
Correct Answer: A
Rationale: Prioritizing relevant information saves time in a busy practice.