Alpha-beta blockers are especially effective to treat hypertension for which ethnic group?
- A. White
- B. Asian
- C. African American
- D. Native American
Correct Answer: C
Rationale: Alpha-beta blockers are particularly effective in African Americans due to their dual mechanism.
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All are explained on pharmacogenetic conditions except
- A. G6PD deficiency
- B. Warfarin insensitivity
- C. Adenosine deaminase deficiency
- D. Malignant hyperthermia
Correct Answer: C
Rationale: Adenosine deaminase deficiency is not typically pharmacogenetic; others are.
Drugs that are designated Schedule II by the U.S. Drug Enforcement Administration:
- A. Are known teratogens during pregnancy
- B. May not be refilled; a new prescription must be written
- C. Have a low abuse potential
- D. May be dispensed without a prescription unless regulated by the state
Correct Answer: B
Rationale: Schedule II drugs (e.g., opioids) require new prescriptions without refills due to high abuse potential, unlike teratogenicity or OTC status .
In response to the patient's question about how to know whether drugs are safe, the nurse explains that all medications undergo rigorous scientific testing controlled by what organization?
- A. Food and Drug Administration (FDA)
- B. Drug Enforcement Agency (DEA)
- C. Centers for Disease Control and Prevention (CDC)
- D. Joint Commission on Accreditation of Healthcare Organizations (JCAHO)
Correct Answer: A
Rationale: The FDA is responsible for controlling and regulating the development and sale of drugs in the United States, allowing new drugs to enter the market only after being subjected to rigorous scientific testing. The DEA regulates and controls the use of controlled substances. The CDC monitors and responds to infectious diseases. The JCAHO is an accrediting body that inspects acute care facilities to ensure minimum standards are met.
A 64-year-old woman with a history of type 2 diabetes is diagnosed with heart failure. Which of the following medications would be a poor choice for controlling her diabetes?
- A. Exenatide
- B. Glyburide
- C. Nateglinide
- D. Rosiglitazone
Correct Answer: D
Rationale: Rosiglitazone can worsen heart failure due to fluid retention and edema.
A potential harmful effect on patients who take some herbal medication is:
- A. Constipation
- B. Lead poisoning
- C. Diarrhea
- D. Life-threatening rash
Correct Answer: B
Rationale: Some herbal products may contain lead contaminants, posing a risk of poisoning.
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