Not a prodrug
- A. Lisinopril
- B. Enalapril
- C. Ramipril
- D. Famotidine
Correct Answer: A
Rationale: Lisinopril is active; others are prodrugs.
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This graph illustrates the dose-response relationship for the effect of the beta agonist isoproterenol on an isolated perfused heart, both alone and in the presence of different fixed concentrations of Drug X. Based upon the data shown, Drug X is most likely a(n):
- A. beta agonist
- B. competitive antagonist
- C. irreversible antagonist
- D. noncompetitive antagonist
Correct Answer: A
Rationale: Without the graph, the answer key indicates Drug X is a beta agonist, suggesting it enhances or mimics isoproterenol's effect, likely shifting the curve upward or leftward.
Which of the following is synthetic mineralocorticoids:
- A. Testosterone
- B. Estradiol
- C. Fludrocortisone
- D. Hydrocortisone
Correct Answer: C
Rationale: Fludrocortisone is a synthetic mineralocorticoid used to mimic aldosterone's effects on sodium retention.
The treatment of hyperlipidemia with gemfibrozil plus lovastatin is associated with a high risk of:
- A. Constipation
- B. Myopathy
- C. Hepatitis
- D. Thrombocytopenia
Correct Answer: B
Rationale: Combining gemfibrozil and statins increases the risk of myopathy due to elevated statin levels.
If an agonist can produce maximal effects and has high efficacy it's called:
- A. Partial agonist
- B. Antagonist
- C. Agonist-antagonist
- D. Full agonist
Correct Answer: D
Rationale: A full agonist achieves maximal receptor activation and effect.
You are the home health nurse caring for a 77-year-old patient with congestive heart failure. When assessing this patient, in relation to their drug therapy, what is one thing that would be important for you to include in your assessment?
- A. Patient's age
- B. Required lifestyle changes
- C. Family members in the community
- D. Compliance with nutritional recommendations
Correct Answer: B
Rationale: Lifestyle changes (e.g., salt restriction) impact CHF drug therapy efficacy and adherence, critical for assessment.
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