Nokea
Aminoglycosides lack activity against streptococci.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Aminoglycosides are effective against some streptococci (e.g., when combined with cell wall-active agents), though they are primarily used for gram-negative bacteria.
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A nurse is teaching a client who has Angina Pectoris and is learning how to treat acute Anginal attacks. The clients asks, What is my next step if I take one tablet, wait 5 minutes, but still have Anginal pain? Which of the following responses should the nurse make?
- A. Take two more sublingual tablets at the same time.
- B. Call the emergency response team.
- C. Take a sustained-release nitroglycerin capsule.
- D. Wait another 5 minutes then take a second sublingual tablet.
Correct Answer: B
Rationale: If pain persists after one dose, call emergency services ; protocol is up to 3 doses 5 minutes apart.
An NP would prescribe the liquid form of ibuprofen for a 6-year-old child because:
- A. Drugs given in liquid form are less irritating to the stomach.
- B. A 6-year-old child may have problems swallowing a pill.
- C. Liquid forms of medication eliminate the concern for first-pass effect.
- D. Liquid ibuprofen does not have to be dosed as often as the tablet form.
Correct Answer: B
Rationale: A 6-year-old may struggle to swallow pills, making liquid ibuprofen more practical . Liquid forms don't eliminate first-pass effect or reduce dosing frequency , and irritation isn't a primary concern here.
A 75-year-old woman with diabetes is taking an oral antidiabetic drug. One day she goes without eating for 18 \mathrm{~h}. Her serum glucose concentration is 48 \mathrm{mg} / \mathrm{dL} (hypoglycemic) upon arrival at the emergency department, where she is deemed to be in critical condition. Which of the following drugs most likely aggravated this fasting hypoglycemia?
- A. Acarbose
- B. Glyburide
- C. Metformin
- D. Pioglitazone
Correct Answer: B
Rationale: Glyburide, a sulfonylurea, can cause severe hypoglycemia, especially during fasting, due to prolonged insulin release.
A nurse is providing instructions to a client who has been experiencing Insomnia and has a new prescription for Temazepam. The nurse should inform the client that which of the following manifestations are adverse effects of temazepam? (Select one that does not apply.)
- A. Incoordination
- B. Hypertension
- C. Amnesia
- D. Sleep driving
Correct Answer: B
Rationale: Temazepam can cause incoordination , sleep driving , and amnesia , common benzodiazepine effects.
During which phase of pharmacokinetics could a significant drug-drug interaction occur, resulting in one drug stimulating or blocking the metabolism of the other drug?
- A. Absorption
- B. Distribution
- C. Biotransformation
- D. Excretion
Correct Answer: C
Rationale: During biotransformation, a drug may be metabolized quicker if taken at the same time as another drug, and higher doses of the drug will be needed to achieve the desired effect. During absorption, one drug can prevent or accelerate absorption of the other drug. During distribution, one drug competes for the protein-binding site of another drug so the second drug cannot be transported to the reactive tissue. During excretion, one drug competes for excretion with the other drug, leading to accumulation and toxic effects of one of the drugs.