Which of the following drug can cause hypoglycemia:
- A. Acarbose
- B. Glipizide
- C. Metformin
- D. Pramlintide
Correct Answer: B
Rationale: Glipizide, a sulfonylurea, can cause hypoglycemia by excessively stimulating insulin release from pancreatic beta cells.
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Which person should be treated with prophylactic antitubercular medication?
- A. A child who attends the same school with a child who has tuberculosis
- B. A nurse who is working in a hospital
- C. An individual who is HIV-positive with a negative TB skin test
- D. A patient who has close contact with someone who has tuberculosis
Correct Answer: D
Rationale: Close contact with TB warrants prophylaxis; school , hospital work , or HIV without exposure don't. Personal contact with a person having a diagnosis of tuberculosis is required to indicate prophylactic treatment with antitubercular therapy.
The following drugs are correctly paired with a clinical use EXCEPT:
- A. Tiludronate to treat Paget's disease of bone
- B. Raloxifene to prevent osteoporosis
- C. Picamycin to treat hypercalcemia
- D. Parathyroid hormone treats hypocalcemia
Correct Answer: D
Rationale: Parathyroid hormone treats osteoporosis, not hypocalcemia; calcitonin or bisphosphonates treat hypocalcemia.
Insulin is used for:
- A. Treatment of diabetes mellitus type I only
- B. Treatment of diabetes mellitus type II only
- C. Treatment of diabetes mellitus type III and IV only
- D. Treatment of diabetes mellitus type I and II
Correct Answer: D
Rationale: Insulin is used for both type 1 (insulin-dependent) and type 2 (when other treatments fail) diabetes.
James tells you that he is confused by his Medicare Part D coverage plan. An appropriate intervention would be:
- A. Order cognitive testing to determine the source of his confusion.
- B. Sit down with him and explain the whole Medicare Part D process.
- C. Refer him to the Medicare specialist in his insurance plan to explain the benefit to him.
- D. Request his son come to the next appointment so you can explain the benefit to him.
Correct Answer: C
Rationale: Referring to a specialist ensures accurate explanation of Medicare Part D.
Once phosphorylated, the intracellular segment of a receptor tyrosine kinase
- A. Activates adenylate cyclase
- B. Causes dissociation of the ligand from an allosteric binding site
- C. Terminates intracellular signaling cascades
- D. Allows docking of intracellular proteins involved in signal transduction
Correct Answer: D
Rationale: Phosphorylation enables docking of signaling proteins, initiating transduction cascades.