Amphetamine is used in
- A. Narcolepsy
- B. Psychosis
- C. Anxiety disorders
- D. Obsessive compulsive neurosis
Correct Answer: A
Rationale: Amphetamine treats narcolepsy by promoting wakefulness.
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Which aminoglycoside is most commonly used in the treatment of cystic fibrosis patients infected with Pseudomonas aeruginosa?
- A. Amikacin
- B. Streptomycin
- C. Tobramycin
- D. Gentamicin
Correct Answer: C
Rationale: Tobramycin is frequently used in cystic fibrosis patients for its efficacy against Pseudomonas aeruginosa, often administered via inhalation or IV.
Nicotine replacement therapy (NRT):
- A. Is widely distributed in the body only when the gum products are used
- B. Does not cross the placenta and so is safe for pregnant women
- C. Delays healing of esophagitis and peptic ulcers
- D. Has no drug interactions when a transdermal patch is used
Correct Answer: C
Rationale: NRT delays GI ulcer healing due to nicotine's effects on acid secretion.
Vera, age 70, has isolated systolic hypertension. Calcium channel blocker dosages for her should be:
- A. Started at about half the usual dosage
- B. Not increased over the usual dosage for an adult
- C. Given once daily because of memory issues in the older adult
- D. Withheld if she experiences gastroesophageal reflux
Correct Answer: A
Rationale: Elderly patients start at half dose due to reduced metabolism and clearance.
Select a suitable therapeutic indication for bethanechol:
- A. To decrease the heart rate
- B. To decrease the blood pressure
- C. For urinary retention
- D. Decrease intraocular pressure
Correct Answer: C
Rationale: Bethanechol, a muscarinic agonist, stimulates bladder contraction for urinary retention.
A patient receiving gentamicin should be monitored for which potential adverse effect?
- A. Nephrotoxicity
- B. Hepatotoxicity
- C. Ototoxicity
- D. Both A and C
Correct Answer: D
Rationale: Gentamicin, an aminoglycoside, commonly causes nephrotoxicity and ototoxicity , requiring monitoring of renal function and hearing.