Nokea
The nurse is teaching a patient who has completed detoxification for alcohol abuse who will be discharged home with a prescription for disulfiram (Antabuse). Which statement by the patient indicates understanding of the teaching?
- A. Even topical products containing alcohol can have serious adverse effects while I am taking this drug
- B. If I experience drowsiness or skin rash, I should discontinue this drug immediately
- C. It is safe to take a product containing alcohol one week after the last dose of disulfiram
- D. This drug acts by blocking the pleasurable effects of alcohol
Correct Answer: A
Rationale: Disulfiram reacts with any alcohol, even topical; effects linger 2 weeks , and it causes aversion, not blocking pleasure . Disulfiram causes an unpleasant and potentially fatal reaction if alcohol is consumed while taking it and can even occur with topical products containing alcohol.
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The patient is prescribed a medication that was just placed in Phase IV study. The patient tells the nurse, This medication is too expensive. Could the doctor order a generic form of this medication? What is the nurse's most accurate response?
- A. Medications are not produced in generic form until the patent expires, which normally takes several years.
- B. You can request the generic form but the binder used may make the drug less effective for this medication.
- C. The generic form of the medication would not be any less expensive because this is a relatively new medication.
- D. Generic medications are lower quality drugs and that would mean you would not be getting the best treatment available.
Correct Answer: A
Rationale: When a new drug enters the market, it is given a time-limited patent; generic forms of the medication cannot be produced until the patent expires. Because no generic version of this drug will exist because it is so new, it is impossible to predict what binder will be used or what the cost would be.
The nurse administers amoxicillin 500 mg. The half-life of this drug is approximately 1 hour. At what point would the drug level in the body be 62.5 mg if the drug was not administered again?
- A. 1 hours after the original dose
- B. 2 hours after the original dose
- C. 3 hours after the original dose
- D. 4 hours after the original dose
Correct Answer: C
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to one-half of the peak level it previously achieved. At a dose of 500 mg the drug level would be 250 mg in 1 hour, 125 mg in 2 hours, 62.5 mg in 3 hours, and 31.25 mg in 4 hours so the correct answer is 3 hours.
A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is a(n):
- A. Cytotoxic hypersensitivity reaction
- B. Immune complex hypersensitivity
- C. Immediate hypersensitivity reaction
- D. Delayed hypersensitivity reaction
Correct Answer: A
Rationale: Neutropenia from Silvadene (silver sulfadiazine) is a Type II cytotoxic reaction , targeting blood cells, not immune complex , immediate , or delayed .
You are designing a drug regimen for a patient. What should be considered?
- A. Quality-of-life issues
- B. Ethnicity of patient
- C. Gender
- D. Quantity-of-life issues
Correct Answer: A
Rationale: Quality-of-life issues ensure the regimen aligns with patient needs and tolerability, enhancing adherence.
A patient receiving gentamicin should be monitored for which potential adverse effect?
- A. Nephrotoxicity
- B. Hepatotoxicity
- C. Ototoxicity
- D. Both A and C
Correct Answer: D
Rationale: Gentamicin, an aminoglycoside, commonly causes nephrotoxicity and ototoxicity , requiring monitoring of renal function and hearing.