Drug which interferes with metabolism of theophylline is:
- A. Erythromycin
- B. Gentamicin
- C. Penicillin
- D. Furazolidone
Correct Answer: A
Rationale: Erythromycin inhibits P-450, increasing theophylline levels.
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Nicotine replacement therapy (NRT):
- A. Is widely distributed in the body only when the gum products are used
- B. Does not cross the placenta and so is safe for pregnant women
- C. Delays healing of esophagitis and peptic ulcers
- D. Has no drug interactions when a transdermal patch is used
Correct Answer: C
Rationale: NRT delays GI ulcer healing due to nicotine's effects on acid secretion.
A nurse is caring for a group of clients who are not protected against Varicella. The nurse should prepare to administer the Varicella vaccine at this time to which of the following clients?
- A. 24-year-old woman in the third trimester of pregnancy
- B. 12-year-old child who has a severe allergy to neomycin
- C. 2-month-old infant who has no health problems
- D. 32-year-old man who has essential hypertension
Correct Answer: D
Rationale: Varicella vaccine is safe for the 32-year-old ; it's contraindicated in pregnancy, neomycin allergy, and infants under 1 year.
Patients should be warned about the overuse of topical wintergreen oil to treat muscle strains, as overapplication can lead to:
- A. Respiratory depression
- B. Cardiac disturbance
- C. Salicylates poisoning
- D. Life-threatening rashes
Correct Answer: C
Rationale: Wintergreen oil contains methyl salicylate, which can cause salicylate poisoning if overused.
Attenuated vaccines are also known as:
- A. Killed vaccines
- B. Booster vaccines
- C. Inactivated vaccines
- D. Live vaccines
Correct Answer: D
Rationale: Attenuated vaccines are live, weakened forms, unlike killed/inactivated or booster-specific vaccines.
Characteristics of vitamin D and its metabolites include which of the following?
- A. Act to decrease serum levels of calcium
- B. Activation of vitamin D receptors in the major cells of
- C. Calcitriol is the major derivative responsible for increasing intestinal absorption of phosphate
- D. Metabolites of vitamin D increase renal excretion of calcium
Correct Answer: C
Rationale: Calcitriol increases intestinal absorption of calcium and phosphate.