Nokea
An outbreak of food poisoning was recorded in an urban settlement. The illness was diagnosed as botulism on the grounds of clinical presentations. What foodstuffs should be chosen for analysis in the first place in order to confirm the diagnosis?
- A. Tinned food
- B. Potatoes
- C. Pasteurized milk
- D. Boiled meat
Correct Answer: A
Rationale: The correct answer is A: Tinned food. Botulism is often caused by the botulinum toxin produced by the bacterium Clostridium botulinum, which can be present in improperly canned foods. Analyzing tinned food allows for direct detection of the toxin or bacteria, confirming the diagnosis. Potatoes, pasteurized milk, and boiled meat are less likely sources of botulism compared to tinned food, making them less suitable for initial analysis in this case.
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Viral capsomeres are composed of subunits called
- A. envelopes.
- B. protomeres.
- C. capsids.
- D. nucleoids.
Correct Answer: B
Rationale: The correct answer is B: protomeres. Viral capsomeres are the building blocks of viral capsids, which are protein coats that enclose and protect the viral genetic material. These capsomeres are made up of smaller subunits called protomeres. Envelopes (A) refer to a lipid membrane surrounding some viruses, not the subunits of capsomeres. Capsids (C) are the protein coats that capsomeres make up, not the subunits themselves. Nucleoids (D) are found in bacterial cells and refer to the region where the genetic material is located, not the subunits of viral capsomeres.
Infectious disease' is:
- A. Clinical term
- B. A term expressing the possibility of developing certain symptoms in an infection
- C. A+B
- D. No correct answer
Correct Answer: C
Rationale: The correct answer is C because "Infectious disease" is a combination of both a clinical term (A) and a term expressing the possibility of developing certain symptoms in an infection (B). Infectious diseases are illnesses caused by pathogenic microorganisms, such as bacteria, viruses, parasites, or fungi, that can spread directly or indirectly from person to person. Therefore, the term encompasses both the clinical aspect of the disease and the potential symptoms that may manifest in an infected individual. Choices A and B alone do not fully capture the comprehensive definition of infectious disease, making C the correct answer. Choice D is incorrect as there is a correct answer in this case.
During examination of the patient's oral cavity a dentist noticed deformation of the teeth and a crescent indentation of the upper right incisor. The teeth are undersized, barrel-shaped – tooth cervix is wider than its edge. The patient uses a hearing aid, suffers from visual impairment. What type of syphilis affects teeth in such way?
- A. Primary
- B. Early congenital
- C. Neurosyphilis
- D. Late congenital
Correct Answer: D
Rationale: The correct answer is D, Late congenital syphilis. This is because the patient presents with Hutchinson's teeth, which are a characteristic feature of late congenital syphilis. Hutchinson's teeth are small, barrel-shaped teeth with a wider cervix and notched incisors. The patient's history of visual impairment and hearing aid use also support the diagnosis of late congenital syphilis, as these are common manifestations of this stage of the disease.
Choice A, Primary syphilis, is incorrect because it typically presents with a painless sore at the site of infection, not dental abnormalities. Choice B, Early congenital syphilis, is incorrect as dental abnormalities in this stage are usually more severe, such as mulberry molars. Choice C, Neurosyphilis, is incorrect as it primarily affects the central nervous system and does not typically present with dental abnormalities.
A patient with suspected liver abscess was admitted to the surgical department. The patient had been staying for a long time on business in one of African countries and fell repeatedly ill with acute gastrointestinal disorders. What protozoal disease may the patient be now ill with?
- A. Amebiasis
- B. Trypanosomosis
- C. Leishmaniasis
- D. Malaria
Correct Answer: A
Rationale: Rationale: The correct answer is Amebiasis (choice A) because the patient's symptoms of acute gastrointestinal disorders and prolonged stay in an African country suggest exposure to Entamoeba histolytica, the causative agent of amebiasis. This protozoal infection commonly occurs in tropical regions, including Africa. Trypanosomosis (choice B) is caused by Trypanosoma species transmitted by tsetse flies, primarily found in sub-Saharan Africa. Leishmaniasis (choice C) is transmitted by sandflies and presents with skin lesions or visceral involvement, not acute gastrointestinal symptoms. Malaria (choice D) is caused by Plasmodium parasites transmitted by mosquitoes and typically presents with fever, not acute gastrointestinal disorders. Therefore, choices B, C, and D are incorrect based on the patient's clinical presentation and travel history.
4 days after a patient received a gunshot wound of the middle third of the thigh soft tissues his condition suddenly began deteriorating. There are complaints of bursting pain in the wound; pain increases during the last 12 hours. Edema of skin and hypodermic tissue quickly grows. Body temperature is 38,2oC, heart rate is 102/min. The wound edges gape, are dull in color; the muscles, viable as of day before, now protrude into the wound, look boiled, are dull in color, have dirty-grey coating and fall apart when being held with forceps. What infection has developed in the wound?
- A. Anaerobic
- B. Aerobic gram-negative
- C. Putrid
- D. Aerobic gram-positive
Correct Answer: A
Rationale: The correct answer is A: Anaerobic infection. The sudden deterioration, bursting pain, edema, foul appearance of wound, and presence of gas are indicative of gas gangrene caused by anaerobic bacteria like Clostridium perfringens. These bacteria thrive in low oxygen environments, such as deep wound tissues. The symptoms align with the classic presentation of gas gangrene, necessitating immediate surgical intervention.
Choice B: Aerobic gram-negative, is incorrect because anaerobic bacteria, not aerobic gram-negative bacteria, are responsible for gas gangrene.
Choice C: Putrid, is incorrect as it is a general term referring to foul-smelling decay and does not specify the type of infection.
Choice D: Aerobic gram-positive, is incorrect as gas gangrene is typically caused by anaerobic bacteria, not aerobic gram-positive bacteria.