Nokea
Angina pectoris, tachycardia, and arrhythmias are possible adverse effects of which of the following drugs?
- A. Clonidine
- B. Phenylephrine
- C. Propranolol
- D. Salbutamol
Correct Answer: D
Rationale: Salbutamol, a beta-2 agonist, can cause cardiac stimulation as a side effect.
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Which statement is not correct about metformin:
- A. Is for internal use only
- B. Reduce weight, apetite
- C. More frequently causes nausea and vomiting comparing with other hypoglicemic drugs
- D. Use for diabetes mellitus type I
Correct Answer: D
Rationale: Metformin is not typically used for type 1 diabetes, which requires insulin, as it acts on insulin sensitivity and hepatic glucose production.
A characteristic that distinguishes true receptors from other drug binding sites present in blood and other biological tissues is the characteristic of:
- A. binding affinity
- B. reversible binding
- C. signal transduction
- D. stereoselective interaction
Correct Answer: B
Rationale: Reversible binding is a key feature of true receptors, distinguishing them from non-specific binding sites like plasma proteins.
Prescribers have been shown to override a medication alert about a patient's allergies when:
- A. The history showed that the patient had tolerated the medication in the past
- B. The benefit outweighed the risk
- C. The medication was therapeutically appropriate and needed
- D. All of the above
Correct Answer: D
Rationale: Prescribers may override alerts if past tolerance, benefit-risk balance, or therapeutic need justifies it.
A nurse is explaining to a young mother why she cannot give her 2-year-old child an adult dose of Tylenol. Which of the following statements would indicate that the mother needs further education?
- A. There could be a time when my child may need a higher dose than normal.'
- B. My baby's dose of Tylenol is based on a healthy adult male.'
- C. My baby can't handle a high dose of Tylenol because her liver may be damaged.'
- D. My child's dose of Tylenol should be based on her weight or age.'
Correct Answer: B
Rationale: A child's dose is never based on an adult's dose. However, on rare occasions a child's dose might be higher than normal if a critical concentration cannot be reached with a smaller dose and a higher dose would not be harmful. Benefits from the increased dosage would have to outweigh the risk for adverse or toxic effects. A child's organs may not be mature enough to handle drugs, causing drug metabolism to be altered. A child's dosages are determined by the age, weight, or body surface.
Patients with iron deficiency will develop:
- A. Hemolytic anemia
- B. Megaloblastic anemia
- C. Macrocytic-hypochromic anemia
- D. Microcytic-hypochromic anemia
Correct Answer: D
Rationale: Iron deficiency causes microcytic-hypochromic anemia due to reduced hemoglobin synthesis.