Bacteria that use oxygen, but only at low concentration, are classified as:
- A. obligate aerobes
- B. microaerophiles
- C. obligate anaerobes
- D. aerotolerant anaerobes
Correct Answer: B
Rationale: The correct answer is B: microaerophiles. These bacteria require oxygen to grow, but only at low concentrations as higher levels can be toxic. They possess enzymes to deal with reactive oxygen species. Obligate aerobes (A) require oxygen for growth, obligate anaerobes (C) cannot survive in the presence of oxygen, and aerotolerant anaerobes (D) can tolerate oxygen but do not use it for growth.
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On microscopic examination of leftovers of the canned meat eaten by patient with severe food toxicoinfection the following was detected: gram-positive bacilli with subterminal staining defect and configuration alteration of bacilli generally resembling a tennis racket. What agent was detected?
- A. C. botulinum
- B. P. vulgaris
- C. E. coli
- D. S. aureus
Correct Answer: A
Rationale: The correct answer is A: C. botulinum. The description of gram-positive bacilli with subterminal staining defect and tennis racket appearance is characteristic of Clostridium botulinum. The subterminal staining defect indicates the presence of spores, a feature of Clostridium species. The tennis racket appearance refers to the characteristic shape of C. botulinum spores. Choice B, P. vulgaris, is a gram-negative bacterium and doesn't match the description. Choice C, E. coli, is a gram-negative bacillus and doesn't exhibit the subterminal staining defect described. Choice D, S. aureus, is a gram-positive cocci and does not resemble the tennis racket appearance described.
Which bacteria are known to produce an endotoxin that can cause septic shock?
- A. Salmonella enterica
- B. Escherichia coli
- C. Pseudomonas aeruginosa
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D because all three bacteria (Salmonella enterica, Escherichia coli, Pseudomonas aeruginosa) are known to produce endotoxins, specifically lipopolysaccharides in their cell walls. Endotoxins are released upon bacterial cell death and can trigger an immune response, leading to septic shock. Salmonella and E. coli are common causes of bacterial infections, while Pseudomonas is associated with nosocomial infections. Therefore, all of the above choices are correct in terms of producing endotoxins that can cause septic shock. Choices A, B, and C are incorrect individually because they do not encompass all the bacteria known to produce endotoxins that can lead to septic shock.
What microorganisms were accounted for in this case?
- A. All bacteria that have grown on a nutrient medium
- B. Opportunistic pathogenic bacteria
- C. Enteropathogenic bacteria and viruses
- D. Colibacilli
Correct Answer: C
Rationale: The correct answer is C because the case specifically mentions "enteropathogenic bacteria and viruses," indicating a focus on these specific microorganisms. Choice A is too broad and includes all bacteria, which is not specified in the case. Choice B mentions opportunistic pathogenic bacteria, which are not necessarily relevant to the case. Choice D specifies colibacilli, which may or may not be relevant to the case, but it is not as specific as choice C which clearly matches the information provided in the case.
Which of the following bacteria can be transmitted via droplets in the air?
- A. Streptococcus pneumoniae
- B. Escherichia coli
- C. Clostridium botulinum
- D. Mycobacterium tuberculosis
Correct Answer: D
Rationale: The correct answer is D: Mycobacterium tuberculosis. This bacterium can be transmitted via droplets in the air through coughing or sneezing. It is spread through respiratory droplets containing the bacteria. Streptococcus pneumoniae (A) is transmitted through direct contact with respiratory secretions, not through droplets in the air. Escherichia coli (B) is commonly transmitted through contaminated food or water, not through the air. Clostridium botulinum (C) is typically transmitted through contaminated food, not via respiratory droplets. Therefore, the correct choice is D as it is the only bacterium listed that can be transmitted via droplets in the air.
Which one is an example of an immunomodulator:
- A. Rifampin
- B. Gamma Interferon
- C. Hexacima
- D. Pentaxim
Correct Answer: B
Rationale: Step-by-step rationale for why B (Gamma Interferon) is the correct answer:
1. Gamma Interferon is a type of immunomodulator that helps regulate the immune response.
2. It activates macrophages and enhances the immune system's ability to fight infections.
3. Rifampin is an antibiotic, not an immunomodulator.
4. Hexacima and Pentaxim are combination vaccines, not immunomodulators.
In summary, Gamma Interferon is the correct answer as it directly influences the immune response, while the other choices are not immunomodulators.