Nokea
Beta-1 receptors are found in the heart and kidney, whereas beta-2 receptors are found in the lungs, gastrointestinal tract, vascular smooth muscle, and skeletal muscle.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: This is a correct description of beta receptor distribution.
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Which classification does meperidine (Demerol) fall under?
- A. I
- B. II
- C. III
- D. IV
Correct Answer: B
Rationale: Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe psychological and physical dependence.
The major disadvantage of celecoxib is:
- A. It is less efficacious compared to non-selective cox-1 inhibitors
- B. It causes more gastrointestinal disturbances
- C. It increases cardiovascular risk of death
- D. It increases risk of kidney disease
Correct Answer: C
Rationale: Celecoxib, a COX-2 inhibitor, increases cardiovascular risk.
Pharmacokinetics is:
- A. The study of biological and therapeutic effects of drugs
- B. The study of absorption, distribution, metabolism and excretion of drugs
- C. The study of mechanism of drugs
- D. The study of methods of new drug development
Correct Answer: B
Rationale: Pharmacokinetics focuses on how the body handles a drug, including absorption, distribution, metabolism, and excretion (ADME), distinguishing it from pharmacodynamics, which studies drug effects.
The clinic nurse is reviewing a teaching plan for the client receiving an antineoplastic medication. When implementing the plan, the nurse tells the client:
- A. To take aspirin (acetylsalicylic acid) as needed for headache
- B. Drink beverages containing alcohol in moderate amounts each evening
- C. Consult with health care providers (HCPs) before receiving immunizations
- D. That it is not necessary to consult HCPs before receiving a flu vaccine at the local health fair
Correct Answer: C
Rationale: Because antineoplastic medications lower the resistance of the body, clients must be informed not to receive immunizations without a HCP's approval. Clients also need to avoid contact with individuals who have recently received a live virus vaccine. Clients need to avoid aspirin and aspirin-containing products to minimize the risk of bleeding, and they need to avoid alcohol to minimize the risk of toxicity and side effects.
A patient needs 500 mL of an infusion over 5 hours. The drop factor is 10 gtt/mL. Calculate the flow rate in drops per minute.
- A. 16.67 gtt/min
- B. 20 gtt/min
- C. 25 gtt/min
- D. 50 gtt/min
Correct Answer: B
Rationale: Flow rate = (500 mL 10 gtt/mL) ÷ (5 60) = 5,000 ÷ 300 = 16.67 gtt/min, rounded to 20 gtt/min.