Nokea
Beta-blockers decrease nocturnal melatonin release, thereby contributing to sleep disturbances.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Beta-blockers, especially lipophilic ones, reduce melatonin release, potentially causing sleep disturbances.
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Phase IV clinical trials in the United States are also known as:
- A. Human bioavailability trials
- B. Post marketing research
- C. Human safety and efficacy studies
- D. The last stage of animal trials before the human trials begin
Correct Answer: B
Rationale: Phase IV is post-marketing research , monitoring drugs after approval, unlike earlier phases or animal studies.
Which of the following glucocorticoid is used for intra-articular injection for treatment of arthrites:
- A. Triamcinolon
- B. Budesonide
- C. Prednisolon
- D. Hydrocortison
Correct Answer: A
Rationale: Triamcinolone is commonly used for intra-articular injections due to its potent anti-inflammatory effects in treating arthritis.
The nurse uses what term to describe the drug level required to have a therapeutic effect?
- A. Critical concentration
- B. Dynamic equilibrium
- C. Selective toxicity
- D. Active transport
Correct Answer: A
Rationale: A critical concentration of a drug must be present before a reaction occurs within the cells to bring about the desired therapeutic effect. A dynamic equilibrium is obtained from absorption of a drug from the site of drug entry, distribution to the active site, metabolism in the liver, and excretion from the body to have a critical concentration. Selective toxicity is the ability of a drug to attach only to those systems found in foreign cells. Active transport is the process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney.
Which action will the nurse take when it is determined that the narcotic count is incorrect while obtaining a medication from the narcotic area?
- A. Determine the cause of the discrepancy at the end of the shift.
- B. Notify the health care provider stat.
- C. Call the nurse from the previous shift to determine if there was a discrepancy earlier.
- D. Report the discrepancy to the charge nurse immediately.
Correct Answer: D
Rationale: Reporting the discrepancy to the charge nurse immediately enables the supervisory staff to narrow the time frame during which a medication was taken and not documented. The discrepancy needs to be addressed immediately, and therefore determining the cause of the discrepancy at the end of the shift is not the most appropriate action for the nurse to take. It is not appropriate to contact the health care provider for an incorrect narcotic count. The count would have been verified at shift change; calling the nurse from the previous shift is not an appropriate action for the nurse to take.
After administering a medication, for what would the nurse assess the patient?
- A. Drug effects
- B. Allergies
- C. Pregnancy
- D. Preexisting conditions
Correct Answer: A
Rationale: After the medication is administered, the nurse assesses the patient for drug effects, both therapeutic and adverse. The nurse would assess the patient for allergies, preexisting conditions, and pregnancy before administering a medication.