Nokea
Binding of drugs to albumin is irreversible.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: False; binding to albumin is reversible, allowing drugs to dissociate and become active or available for elimination.
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Please select a correct statement:
- A. The risk of glaucoma and cataract increases with long-term use of steroids
- B. in the case of long term corticosteroid therapy rapid withdrawal increase the risk of hypertonic crisis
- C. Prescribing steroids in the case of transplantation stimulated transplant rejection
- D. In the bone steroids decrease osteoclasts and increase osteoblasts
Correct Answer: A
Rationale: Long-term steroid use increases the risk of glaucoma and cataracts due to ocular effects.
Which of the following create a higher risk for digoxin toxicity? Both the cause and the reason for it must be correct.
- A. Older adults because of reduced renal function
- B. Administration of aldosterone antagonist diuretics because of decreased potassium levels
- C. Taking an antacid for gastroesophageal reflux disease because it increases the absorption of digoxin
- D. Doses between 0.25 and 0.5 mg/day
Correct Answer: A
Rationale: Older adults have reduced renal clearance, increasing digoxin toxicity risk.
Which antiepileptic drug does not act as GABA agonist?
- A. Phenytoin
- B. Sodium valproate
- C. Diazepam
- D. Phenbarbitone
Correct Answer: A
Rationale: Phenytoin blocks sodium channels, not GABA-related.
59 old year female hospitalized in emergency department with confusion and breathlessness. Physical examination reveals: tachycardia, tachypnea and disorientation. Patient has diabetes type 2 and remember that she has taken a drug in the morning. Which of the following can cause the above mentioned symptoms:
- A. Acarbose
- B. Glipizide
- C. Glucagon
- D. Metformin
Correct Answer: B
Rationale: Glipizide can cause hypoglycemia leading to confusion, tachycardia, and breathlessness, especially if taken without food.
Salicylic acid is prescribed for a client with a diagnosis of psoriasis. The nurse monitors the client, knowing that which of the following would indicate the presence of systemic toxicity from this medication?
- A. Tinnitus
- B. Diarrhea
- C. Constipation
- D. Decreased respirations
Correct Answer: A
Rationale: Salicylic acid is absorbed readily through the skin, and systemic toxicity (salicylism) can result. Symptoms include tinnitus, dizziness, hyperpnea, and psychological disturbances. Constipation and diarrhea are not associated with salicylism.