Nokea
Carbamazepine has a Black Box Warning due to life-threatening:
- A. Renal toxicity, leading to renal failure
- B. Hepatotoxicity, leading to liver failure
- C. Dermatologic reaction, including Steven's Johnson and toxic epidermal necrolysis
- D. Cardiac effects, including supraventricular tachycardia
Correct Answer: C
Rationale: Carbamazepine's Black Box Warning highlights severe skin reactions like SJS/TEN.
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A nurse reviewing a client's medical record notes a new prescription for verifying the trough level of the client's medication. Which of the following actions should the nurse take?
- A. Obtain a blood specimen immediately prior to administering the next dose of medication.
- B. Verify that the client has been taking the medication for 24 hour before obtaining a blood specimen.
- C. Ask the client to provide a urine specimen after the next dose of medication.
- D. Administer the medication, and obtain a blood specimen 30 min late
Correct Answer: A
Rationale: Trough levels are measured just before the next dose to assess the lowest drug concentration in the blood.
It is reasonable to add to a Helicobacter pylori treatment regimen to improve eradication rates of H. pylori.
- A. Probiotics
- B. Omega-3 fatty acids
- C. Plant sterols
- D. Fiber
Correct Answer: A
Rationale: Probiotics improve H. pylori eradication rates by supporting gut health during treatment.
Which of the following is CORRECT about aspirin poisoning?
- A. Is rarely seen in cases of chronic use
- B. It does not affect body temperature
- C. It is treated by administration of intravenous sodium bicarbonate
- D. The earliest sign is hypoventilation
Correct Answer: C
Rationale: Sodium bicarbonate enhances aspirin excretion by alkalinizing urine.
The anthelminthic whose dose is 400 gms stat for most worm infestation:
- A. Piperazine
- B. Mebendazole
- C. Albendazole
- D. Levamisole
Correct Answer: C
Rationale: Albendazole is commonly prescribed as a single 400 mg dose (stat) for most intestinal worm infestations, such as ascariasis and hookworm, due to its broad-spectrum efficacy.
Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to prescribing:
- A. Erythromycin
- B. Digoxin
- C. Cetuximab
- D. Rifampin
Correct Answer: C
Rationale: FDA requires pharmacogenetic testing for cetuximab to check EGFR status, not for erythromycin, digoxin, or rifampin.