Nokea
Carbohydrate absorption:
- A. all glucose, galactose and fructose is co-transported with Na by the SGLT-2 transporter into enterocytes
- B. all glucose/galactose and fructose is transported across the basolateral membrane by GLUT2
- C. fructose absorption is a secondary active transport mechanism
- D. absorption is decreased by insulin
Correct Answer: B
Rationale: Rationale:
- GLUT2 transporter on basolateral membrane transports glucose, galactose, and fructose.
- SGLT-2 transporter on apical membrane co-transports glucose and galactose with Na.
- Fructose absorption is via facilitated diffusion, not secondary active transport.
- Insulin increases, not decreases, carbohydrate absorption.
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A nursing health history of a client suspected of having Cushing syndrome must include assessment of
- A. increased pigmentation
- B. decreased urinary output
- C. changes in body structure and weight
- D. increased thickening and coarsening of skin
Correct Answer: C
Rationale: Changes in body structure and weight, such as fat redistribution and weight gain, are key signs of Cushing syndrome.
Injecting cocaine may cause a hypertensive crisis or stroke, and if the cocaine is inhaled frequently, it may destroy the tissues in the nose. Which of the following best describes how cocaine causes these adverse effects?
- A. Blocks alpha adrenergic receptors
- B. Blocks muscarinic receptors for ACh
- C. Blocks reuptake of noradrenaline released from adrenergic nerves
- D. Depletes norepinephrine from adrenergic nerve endings
Correct Answer: C
Rationale: Cocaine blocks the reuptake of noradrenaline from adrenergic nerves, leading to excessive stimulation of adrenergic receptors. This causes increased blood pressure, which can result in a hypertensive crisis or stroke. Additionally, the vasoconstrictive effects of excess noradrenaline can lead to tissue damage in the nose when cocaine is inhaled frequently. Choices A and B are incorrect because cocaine does not directly block alpha adrenergic or muscarinic receptors. Choice D is incorrect because cocaine does not deplete norepinephrine from adrenergic nerve endings but rather increases its concentration by blocking reuptake.
Hormones often cause a cell to elicit multiple responses; this is because ________.
- A. there are thousands of receptors on the cell membrane
- B. the receptors bind to several hormones at the same time
- C. the protein kinases are rapidly metabolized
- D. during protein kinase activation, enzymes phosphorylate many other enzymes
Correct Answer: D
Rationale: The correct answer is D because during protein kinase activation, enzymes phosphorylate many other enzymes, leading to a cascade of signaling events that can trigger multiple responses in a cell. This process amplifies and diversifies the cellular response to hormones.
A: Choice A is incorrect because the number of receptors on the cell membrane does not directly relate to the ability of hormones to elicit multiple responses.
B: Choice B is incorrect because receptors typically bind to one hormone molecule at a time, not multiple hormones simultaneously.
C: Choice C is incorrect because the rapid metabolism of protein kinases does not directly explain why hormones can elicit multiple responses in a cell.
Identify the endocrine gland that is located atop the kidneys.
- A. Adrenal gland
- B. Hypothalamus
- C. Pancreas
- D. Thyroid gland
Correct Answer: A
Rationale: The correct answer is A: Adrenal gland. The adrenal gland is located atop the kidneys and is responsible for producing hormones such as adrenaline and cortisol. This gland plays a crucial role in the body's stress response and regulation of metabolism. The other choices are incorrect because the hypothalamus is located in the brain and regulates hormone secretion, the pancreas is located in the abdomen and is involved in insulin production, and the thyroid gland is located in the neck and controls metabolism.
What is the stimulus for the release of insulin?
- A. Low plasma levels of calcium
- B. High plasma levels of potassium
- C. High plasma levels of glucose
- D. Low blood volume
Correct Answer: C
Rationale: The correct answer is C: High plasma levels of glucose. When blood glucose levels rise after a meal, pancreatic beta cells sense this increase and release insulin to facilitate glucose uptake into cells for energy production or storage. This is known as the glucose-stimulated insulin release mechanism. Low plasma levels of calcium (choice A), high plasma levels of potassium (choice B), and low blood volume (choice D) do not directly stimulate insulin release and are unrelated to the regulation of insulin secretion.