Nokea
Cholinergic blockers are used to:
- A. Counteract the extrapyramidal symptoms (EPS) effects of phenothiazines
- B. Control tremors and relax smooth muscle in Parkinson's disease
- C. Inhibit the muscarinic action of ACh on bladder muscle
- D. All of the above
Correct Answer: D
Rationale: Cholinergic blockers address EPS, Parkinson's symptoms, and bladder overactivity.
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A nursing student is reviewing information about the Controlled Substances Act of 1970. The student would expect to find which of the following as being regulated for drugs classified as controlled substances? Select one that does not apply
- A. Manufacturing
- B. Elimination
- C. Distribution
- D. Dispensing the drug
Correct Answer: B
Rationale: The Controlled Substances Act of 1970 regulates the manufacture, distribution, and dispensing of drugs classified as controlled substances. Elimination refers to the excretion of drugs from the body, a pharmacokinetic activity. The act does not address formulation of the drug.
Aminoglycosides work by irreversibly binding to the 30 ribosomal subunit.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Aminoglycosides irreversibly bind to the 30S ribosomal subunit, disrupting bacterial protein synthesis and leading to bactericidal effects.
Jamie has fractured his ankle and has received a prescription for acetaminophen and hydrocodone (Vicodin). Education when prescribing Vicodin includes:
- A. It is okay to double the dose of Vicodin if the pain is severe
- B. Vicodin is not habit-forming
- C. He should not take any other acetaminophen-containing medications
- D. Vicodin may cause diarrhea; increase his fluid intake
Correct Answer: C
Rationale: Avoiding extra acetaminophen prevents overdose; Vicodin is habit-forming , and constipation, not diarrhea , is common.
Amphetamine should not be taken with.....
- A. Paracetamol
- B. Aspirin
- C. MAO inhibitors
- D. Benzimidazole
Correct Answer: C
Rationale: Amphetamines combined with MAO inhibitors can cause a hypertensive crisis due to excessive catecholamine accumulation, a well-known dangerous interaction.
A nurse working as a member of a research team is exploring the unique differences in drug response that each individual possesses based on his or her genetic makeup. This area of study is called:
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a person's unique genetic makeup. Pharmacotherapeutics is the branch of pharmacology that deals with the use of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes any costs involved in drug therapy.