Commercials on TV for erectile dysfunction (ED) medications warn about mixing them with nitrates. Why?
- A. Increased risk of priapism
- B. Profound hypotension
- C. Development of blue discoloration to the visual field
- D. Inactivation of the ED medication effect
Correct Answer: B
Rationale: ED drugs (PDE5 inhibitors) with nitrates cause severe vasodilation, leading to hypotension.
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Which of the following statements about Thalidomide is INCORRECT?
- A. It is anti angiogenic
- B. It is anti inflammatory
- C. It is immunomodulatory
- D. It is mitogenic
Correct Answer: D
Rationale: Thalidomide is not mitogenic; it inhibits cell proliferation.
What must the nurse have before administering any medication? (Select one that does not apply.)
- A. A current license to practice
- B. A medication order signed by a practitioner licensed with prescription privileges
- C. Knowledge of the medication
- D. Consultation with a pharmacist
Correct Answer: D
Rationale: Physicians must be licensed to prescribe medications; nurses must be licensed to administer medications. Safe medication administration includes knowledge of the medication, pathophysiology of patient diagnoses, and pharmacodynamics of the ordered medication on the pathophysiology. It is not necessary for the nurse to consult with a pharmacist each time medication is to be administered to a patient.
A nurse is teaching a client who has schizophrenia strategies to cope with anticholinergic effects of Fluphenazine. Which of the following should the nurse suggest to the client to minimize anticholinergic effects?
- A. Take the medication in the morning to prevent insomnia.
- B. Chew sugarless gum to moisten the mouth.
- C. Use cooling measures to decrease fever.
- D. Take an antacid to relieve nausea
Correct Answer: B
Rationale: Chewing gum relieves dry mouth, a common anticholinergic effect of fluphenazine.
A nurse is caring for a patient who has recently moved from Vermont to south Florida. The patient has been on the same antihypertensive drug for 6 years and has had stable blood pressures and no side effects. Since her move, however, she reports having 'dizzy spells and weakness' and feels that the drug is no longer effective. The nurse knows that one possible reason for the change in the effectiveness of the drug could be which of the following?
- A. The impact of the placebo effect on the patient's response
- B. The accumulative effect of the drug if it has been taken for many years
- C. The impact of the warmer environment on the patient's physical state
- D. Problems with patient compliance with the drug regimen while on vacation
Correct Answer: C
Rationale: Antihypertensive drugs work to decrease the blood pressure. When a patient goes to a climate that is much warmer than usual, blood vessels dilate and the blood pressure falls. If a patient is taking an antihypertensive drug and enters a warmer climate, there is a chance that the patient's blood pressure will drop too low, resulting in dizziness and feelings of weakness. Most antihypertensives are metabolized and excreted and do not accumulate in the body. Patients must be very compliant with their drug regimen while on vacation. After several years on an antihypertensive drug, the effects of that drug are known; therefore, the placebo effect should not be an issue.
A nurse is caring for a client who has a prescription for Bethanechol to treat urinary retention. The nurse should recognize that which of the following findings is a manifestation of muscarinic stimulation?
- A. Dry mouth
- B. Hypertension
- C. Excessive perspiration
- D. Fecal impaction
Correct Answer: C
Rationale: Bethanechol stimulates muscarinic receptors, causing excessive perspiration , not dry mouth.