What is the responsibility of the nurse related to the patient's drug therapy? (Select all that apply.)
- A. Teaching the patient how to cope with therapy to ensure the best outcome
- B. Providing therapy as well as medications
- C. Changing of therapy routines
- D. Altering the drug regimen to optimize outcome
Correct Answer: A
Rationale: Nurses teach patients, evaluate therapy effectiveness, but do not alter regimens (physician's role) or provide therapy beyond medication administration.
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Which statement is false of Domperidone
- A. Chemically related to haloperidol
- B. Pharmacologically related to metoclopramide
- C. Extra pyramidal symptoms are common
- D. It counteracts the emetic action but not the therapeutic effect in parkinsonism
Correct Answer: C
Rationale: Domperidone rarely causes extrapyramidal symptoms as it doesn't cross the blood-brain barrier.
The patient is a 6-year-old child who is taking 125 mg of amoxicillin every 6 hours. Assuming that the half-life of Amoxicillin is 3 hours, how much Amoxicillin would be in the child's body at the time of the next administration of the drug?
- A. 62.5 mg
- B. 46.875 mg
- C. 31.25 mg
- D. 15.625 mg
Correct Answer: C
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to 1 half the peak level it previously achieved. Option A would occur at 3 hours after the original dose of amoxicillin. Option B would occur 4½ hours after the original dose. Option C would occur at 6 hours after the original dose. Option D would occur at 7½ hours after the original dose.
Which of the following is a carbapenem antibiotic?
- A. Meropenem
- B. Ceftriaxone
- C. Amoxicillin
- D. Aztreonam
Correct Answer: A
Rationale: Meropenem is a carbapenem, a broad-spectrum beta-lactam antibiotic, unlike ceftriaxone (cephalosporin) or amoxicillin (penicillin).
All are pro drugs except
- A. Sulindac
- B. Codeine
- C. Talampicillin
- D. Chlorpromazine
Correct Answer: D
Rationale: Chlorpromazine is active as is; others are prodrugs.
All of the following pairs of drug compete for the same receptors except
- A. Ranitidine and histamine
- B. Metoclopramide and dopamine
- C. Dicyclomine and adrenaline
- D. Benzhexol and acetylcholine
Correct Answer: C
Rationale: Dicyclomine (anticholinergic) and adrenaline (adrenergic) act on different receptors; others compete at the same receptor sites.
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