Nokea
Common causes of jaundice in a 12-hour-old neonate include:
- A. Glucose-6-phosphate dehydrogenase deficiency
- B. Rhesus isoimmunisation
- C. Crigler-Najjar syndrome type II
- D. Choledochal cyst
Correct Answer: B
Rationale: Rhesus isoimmunisation can cause severe hemolysis in neonates, leading to early-onset jaundice within the first 12 hours of life.
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Maltese crosses' are identified in the urinary sediments in
- A. Niemann Pick disease
- B. Gaucher disease
- C. Krabbe's disease
- D. Fabry disease
Correct Answer: D
Rationale: Fabry disease is characterized by the presence of 'Maltese crosses' in urinary sediments due to glycosphingolipid accumulation.
The best test to confirm the diagnosis of tuberculosis is:
- A. Chest X-ray
- B. Sputum culture
- C. Skin test
- D. Blood culture
Correct Answer: B
Rationale: Sputum culture is the gold standard for diagnosing tuberculosis, as it can identify Mycobacterium tuberculosis bacteria in a sample.
The following criteria are indications for further investigation of premature ventricular contractions (PVCs) that could require suppressive therapy EXCEPT
- A. multiform PVCs
- B. disappear during exercise
- C. R-on-T phenomenon
- D. extreme frequency of beats
Correct Answer: B
Rationale: PVCs that disappear during exercise are less concerning and do not necessarily require suppressive therapy.
A child born with Trisomy 21 should be evaluated for which associated cardiac manifestation?
- A. Systemic hypertension
- B. Congenital heart defect
- C. Hyperlipidemia
- D. Cardiomyopathy
Correct Answer: B
Rationale: Children with Trisomy 21 (Down syndrome) have a high incidence of congenital heart defects, such as atrioventricular septal defects, and should be evaluated for these conditions.
Rocker bottom feet and polyvalvular dysplasia are characteristic of which of the following?
- A. Trisomy 19
- B. Trisomy 18
- C. Trisomy 13
- D. Trisomy 21
Correct Answer: B
Rationale: Rocker bottom feet and polyvalvular dysplasia are classic signs of trisomy 18 (Edwards syndrome), a condition that involves multiple congenital anomalies.