Nokea
Commonly used anti-epileptic drugs in children include:
- A. Sodium valproate
- B. Lamotrigine
- C. Topiramate
- D. Phenytoin
Correct Answer: A
Rationale: The correct answer is A because sodium valproate is a commonly used anti-epileptic drug in children. The other options (b-e) are also used but are not the most common first-line treatment.
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Regarding body iron stores:
- A. Serum ferritin is a poor guide to iron stores
- B. A healthy young man will have more iron stored as ferritin than in the circulating red cell mass
- C. Iron is the stimulant for ferritin production
- D. In iron deficiency, stores of haemosiderin are mobilised before ferritin
Correct Answer: C
Rationale: Iron is a key regulator for ferritin production, and as iron levels rise, ferritin synthesis is stimulated to store excess iron.
The parent of a 1-year-old child with tetralogy of Fallot asks the nurse, “Why do my child’s fingertips look like that?†On what understanding does the nurse base a response?
- A. Clubbing occurs as a result of untreated congestive heart failure.
- B. Clubbing occurs as a result of a left-to-right shunting of blood.
- C. Clubbing occurs as a result of decreased cardiac output.
- D. Clubbing occurs as a result of chronic hypoxia.
Correct Answer: D
Rationale: Clubbing of the fingers develops in response to chronic hypoxia.
A 12-year-old child whose weight and body mass index (BMI) are in the 75th percentile has a diastolic blood pressure that is between the 95th and 99th percentiles for age, sex, and height on three separate occasions. Which test will be prescribed for this child initially?
- A. complete blood count
- B. erythrocyte sedimentation rate
- C. urinalysis and electrolytes
- D. renal function
Correct Answer: C
Rationale: Since the majority of children with stage 1 or 2 hypertension have renal or renovascular causes for elevated BP, renal function and plasma renin tests should be performed.
Triggers of the alternate pathway of complement are:
- A. Bacterial lipopolysaccharide
- B. Interleukin 2
- C. Macrophages
- D. Properdin
Correct Answer: A
Rationale: The correct answer is A because bacterial lipopolysaccharide is a known trigger of the alternate complement pathway. The other options (b-e) are not primary triggers.
The following cardiac lesions are at increased risk for bacterial endocarditis EXCEPT
- A. mitral insufficiency
- B. aortic stenosis
- C. atrial septal defect seccundum
- D. coarctation of the aorta
Correct Answer: C
Rationale: ASD seccundum is generally not considered a high-risk lesion for bacterial endocarditis.