Nokea
Congenital CMV infections are caused by:
- A. coronavirus
- B. herpes simplex virus
- C. cytomegalovirus
- D. Epstein-Barr virus
Correct Answer: C
Rationale: The correct answer is C: cytomegalovirus (CMV). Congenital CMV infections are caused by the transmission of CMV from a pregnant woman to her fetus. CMV is a type of herpes virus, not a coronavirus (A), herpes simplex virus (B), or Epstein-Barr virus (D). CMV is known to cause serious health issues in newborns, making it crucial to identify and manage during pregnancy.
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Which form of human plague is present with high fever and large lymphadenopathies (buboes). The case fatality in untreated cases may reach 60%.
- A. Bubonic plague
- B. Pneumonic plague
- C. Gastrointestinal plague
- D. Septicemic plague
Correct Answer: A
Rationale: The correct answer is A: Bubonic plague. Bubonic plague is characterized by high fever and large swollen lymph nodes (buboes). The case fatality rate in untreated cases can reach 60%. This form of plague is typically transmitted through the bite of an infected flea.
B: Pneumonic plague presents with respiratory symptoms and is transmitted through respiratory droplets.
C: Gastrointestinal plague is not a recognized form of plague.
D: Septicemic plague is a severe form of plague where the bacteria multiply in the bloodstream. It may not always present with buboes.
Which of the following bacteria is associated with food poisoning caused by improperly canned foods?
- A. Clostridium botulinum
- B. Escherichia coli
- C. Salmonella enterica
- D. Vibrio cholerae
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum. This bacterium is associated with food poisoning from improperly canned foods due to its ability to produce botulinum toxin, a potent neurotoxin that causes botulism. Improper canning allows spores of Clostridium botulinum to survive and germinate, producing the toxin in anaerobic conditions. The other choices are incorrect because Escherichia coli, Salmonella enterica, and Vibrio cholerae are not typically associated with food poisoning from improperly canned foods. Escherichia coli and Salmonella are more commonly linked to contaminated water or undercooked food, while Vibrio cholerae causes cholera primarily through contaminated water sources.
A man died from an acute disease characterized by fever, jaundice, hemorrhagic rash, and acute renal insufficiency. Histological examination revealed spiral bacteria shaped like 'C' and 'S' letters. Identify the pathogen.
- A. Leptospira
- B. Treponema
- C. Borrelia
- D. Spirochaeta
Correct Answer: A
Rationale: The correct answer is A: Leptospira. Leptospira is a spiral-shaped bacterium that causes a disease known as leptospirosis, characterized by fever, jajsondice, hemorrhagic rash, and renal insufficiency. The characteristic spiral shape of the bacteria, resembling 'C' and 'S' letters, is a key identifying feature. Leptospira is commonly associated with contaminated water sources and can be transmitted to humans through contact with infected animals or water.
Summary of other choices:
B: Treponema - Treponema pallidum is the causative agent of syphilis, which does not typically present with the combination of symptoms described in the question.
C: Borrelia - Borrelia species are associated with Lyme disease and relapsing fever, but do not match the specific symptoms and histological appearance described in the question.
D: Spirochaeta - Spirochaeta is a genus of bacteria, but specific species within
A patient who has been taking tetracycline for a long time has developed candidosis of mucous membranes. What drug shoul administered for its treatment?
- A. Itraconazole
- B. Griseofulvin
- C. Nitrofungin
- D. Amphotericin
Correct Answer: A
Rationale: The correct answer is A: Itraconazole. Itraconazole is an antifungal medication commonly used to treat candidosis. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This action disrupts the integrity of the fungal cell membrane, leading to cell death. Griseofulvin (B) is primarily used to treat fungal infections of the skin and nails, not mucous membranes. Nitrofungin (C) is not commonly used for candidosis treatment. Amphotericin (D) is a potent antifungal medication but is typically reserved for severe or systemic fungal infections due to its potential side effects.
Bacteriology testing is one of the methods for laboratory diagnostics of diphtheria. To grow the
- A. diphtheriae, it is necessary to know the proper conditions for causative agent cultivation. What nutrient media are optimal for Corynebacterium diphtheriae cultivation?
- B. Sugar meat pepton broth, sugar meat pepton agar
- C. Salt egg yolk agar
- D. Endomedium, Ploskirev medium
Correct Answer: B
Rationale: The correct answer is B: Sugar meat pepton broth, sugar meat pepton agar. These nutrient media are optimal for Corynebacterium diphtheriae cultivation due to their ability to support the growth of this bacterium. Sugar meat pepton broth provides a liquid medium with essential nutrients, while sugar meat pepton agar provides a solid surface for bacterial growth and isolation.
Incorrect choices:
A: Diphtheriae does not require specific conditions for cultivation.
C: Salt egg yolk agar is not commonly used for Corynebacterium diphtheriae.
D: Endomedium and Ploskirev medium are not standard media for diphtheria testing.