Endocrine System Test Questions Related

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Drug X causes an increase in blood pressure and a decrease in heart rate when administered to a patient intravenously. If an antagonist at ganglionic nicotinic receptors is administered first, drug X causes an increase in blood pressure and an increase in heart rate. Drug X most likely is

  • A. Propranolol
  • B. Norepinephrine
  • C. Isoproterenol
  • D. Terbutaline
Correct Answer: B

Rationale: The correct answer is B: Norepinephrine. When an antagonist at ganglionic nicotinic receptors is administered, it blocks the inhibitory effect on sympathetic tone. Since norepinephrine is a sympathetic neurotransmitter that increases blood pressure and heart rate, it is likely that Drug X is norepinephrine. Propranolol (A) is a beta-blocker that decreases heart rate, Isoproterenol (C) is a beta-agonist that increases heart rate, and Terbutaline (D) is a beta-agonist that also increases heart rate. These choices do not align with the observed effects of Drug X when the ganglionic nicotinic receptor antagonist is administered.