During assessment of a patient with osteoarthritis pain, the nurse knows that which condition is a contraindication to the use of nonsteroidal anti-inflammatory drugs (NSAIDs)?
- A. Renal disease
- B. Diabetes mellitus
- C. Headaches
- D. Rheumatoid arthritis
Correct Answer: A
Rationale: Contraindications to NSAIDs include known drug allergy and conditions that place a patient at risk for bleeding, such as vitamin K deficiency, and peptic ulcer disease. Patients with documented aspirin allergy must not receive NSAIDs. Other common contraindications are those that apply to most drugs, including severe renal or hepatic disease.
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The nurse is reviewing the history of a patient who has a new order for a nonsteroidal anti-inflammatory drug (NSAID). Which conditions, if present, are contraindications to the use of NSAIDs? (Select all that apply.)
- A. Vitamin K deficiency
- B. Arthralgia
- C. Peptic ulcer disease
- D. Documented aspirin allergy
Correct Answer: A,C,D
Rationale: Contraindications to NSAIDs include known drug allergy as well as conditions that place the patient at risk for bleeding, such as vitamin K deficiency and peptic ulcer disease. Patients with documented aspirin allergy should not receive NSAIDs. NSAIDs may be used to treat arthralgia.
There is a new order for Naproxen 250 mg PO twice daily. The drug is available as an oral suspension that contains 125 mg/5 mL. Identify how many milliliters the nurse will administer for 1 dose of this medication.
Correct Answer: 10 mL
Rationale: Calculate dose: 125 mg:5 mL::250 mg:x mL. (125 ?? x) = (5 ?? 250); 125x = 1250; x = 10 mL.
The nurse is reviewing the therapeutic effects of nonsteroidal anti-inflammatory drugs (NSAIDs), which include which effect?
- A. Anxiolytic
- B. Sedative
- C. Antipyretic
- D. Antimicrobial
Correct Answer: C
Rationale: NSAIDs have antipyretic effects but not the other effects listed.
A patient has used enteric aspirin for several years as treatment for osteoarthritis. However, the symptoms are now worse and she is given a prescription for a nonsteroidal anti-inflammatory drug and misoprostol, also called Cytotec. The patient asks the nurse, 'Why am I now taking two pills for arthritis?' What is the nurse's best response?
- A. Cytotec will also reduce the symptoms of your arthritis.
- B. Cytotec helps the action of the NSAID so that it will work better.
- C. Cytotec reduces the mucous secretions in the stomach, which reduces gastric irritation.
- D. Cytotec may help to prevent gastric ulcers that may occur in patients taking NSAIDs.
Correct Answer: D
Rationale: Cytotec inhibits gastric acid secretions and stimulates mucous secretions; it has proved successful in preventing the gastric ulcers that may occur in patients taking NSAIDs.
The nurse notes in a patient's medication history that the patient is taking allopurinol. Based on this finding, the nurse interprets that the patient has which disorder?
- A. Rheumatoid arthritis
- B. Gout
- C. Osteoarthritis
- D. Systemic lupus erythematosus
Correct Answer: B
Rationale: Allopurinol is indicated for the treatment of gout but is not indicated for the other disorders listed.
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