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During drug therapy for pneumonia, a female patient develops a vaginal superinfection. The nurse explains that this infection is caused by which of these?
- A. Large doses of antibiotics that kill normal flora
- B. The infection spreading from the lungs to the new site of infection
- C. Resistance of the pneumonia-causing bacteria to the drugs
- D. An allergic reaction to the antibiotics
Correct Answer: A
Rationale: Normally occurring bacteria are killed during antibiotic therapy, allowing other flora to take over and resulting in superinfections.
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The nurse is reviewing the culture results of a patient with an infection, and notes that the culture indicates a gram-positive organism. Which generation of cephalosporin is most appropriate for this type of infection?
- A. First-generation
- B. Second-generation
- C. Third-generation
- D. Fourth-generation
Correct Answer: A
Rationale: First-generation cephalosporins provide excellent coverage against gram-positive bacteria but limited coverage against gram-negative bacteria.
A patient will be receiving amoxicillin suspension 300 mg via a gastrostomy tube every 8 hours. The medication comes in a bottle that contains 400 mg/5 mL. Identify how many milliliters the nurse will administer with each dose. (record answer using one decimal place)
Correct Answer: 3.8 mL
Rationale: 400 mg:5 mL::300 mg:x mL. Solve for x: (400 ?? x) = (5 ?? 300); 400x = 1500; x = 3.75, rounding to 3.8; administer 3.8 mL.
A patient tells the nurse that he is having nausea and decreased appetite during drug therapy with a tetracycline antibiotic. Which statement is the nurse's best advice to the patient?
- A. Take it with cheese and crackers or yogurt.
- B. Take each dose with a glass of milk.
- C. Take an antacid with each dose as needed.
- D. Drink a full glass of water with each dose.
Correct Answer: D
Rationale: Oral doses should be given with at least 8 ounces of fluids and food to minimize gastrointestinal upset. Antacids and dairy products will bind with the tetracycline and make it inactive.
The nurse is providing teaching to a patient taking an oral tetracycline antibiotic. Which statement by the nurse is correct?
- A. Avoid direct sunlight and tanning beds while on this medication.
- B. Milk and cheese products result in increased levels of tetracycline.
- C. Antacids taken with the medication help to reduce gastrointestinal distress.
- D. Take the medication until you are feeling better.
Correct Answer: A
Rationale: Drug-related photosensitivity occurs when patients take tetracyclines, and it may continue for several days after therapy. Milk and cheese products result in decreased levels of tetracycline when the two are taken together. Antacids also interfere with absorption and should not be taken with tetracycline. Counsel patients to take the entire course of prescribed antibiotic drugs, even if they feel that they are no longer ill.
The nurse is monitoring for therapeutic results of antibiotic therapy in a patient with an infection. Which laboratory value would indicate therapeutic effectiveness of this therapy?
- A. Increased red blood cell count
- B. Increased hemoglobin level
- C. Decreased white blood cell count
- D. Decreased platelet count
Correct Answer: C
Rationale: Decreased white blood cell counts are an indication of reduction of infection and are a therapeutic effect of antibiotic therapy.