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Foam cells are a prominent feature of atherosclerosis. Question: Foam cells develop as a result of which of the following options?
- A. Uptake of LDL in macrophages
- B. Uptake of LDL by LDL-R
- C. Uptake of ox-LDL by scavenger receptors
- D. Uptake of LDL by scavenger receptors
Correct Answer: C
Rationale: Foam cells ox-LDL via scavenger receptors stuff macrophages, not plain LDL or LDL-R. Nurses see this, a chronic plaque birth.
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Hyperglycaemia is involved in cardiovascular complications in diabetes. There are several mechanisms through which high glucose levels in endothelial cells can lead to complications. Question: Which mechanism is NOT directly associated with cardiovascular complications in diabetes?
- A. Activation of PKC
- B. AGE pathway
- C. Sorbitol pathway
- D. Fatty acid oxidation
Correct Answer: D
Rationale: High glucose trashes vessels PKC, AGEs, sorbitol clog the works, but fatty acid burn's metabolic, not direct CV. Nurses spot this, a chronic heart sidestep.
For a patient who is experiencing side effects of radiation therapy, which task would be the most appropriate to delegate to the nursing assistant?
- A. Assist the patient to identify patterns of fatigue
- B. Recommend participation in a walking program
- C. Report the amount and type of food consumed from the tray
- D. Check the skin for redness and irritation after the treatment
Correct Answer: C
Rationale: Radiation side effects like fatigue and anorexia benefit from team care. Reporting food consumed from the tray suits nursing assistants observing and relaying intake data supports nutrition monitoring without requiring clinical judgment. Identifying fatigue patterns demands analysis, a nurse's role to adjust care plans. Recommending exercise exceeds assistants' scope physicians or RNs initiate such advice. Checking skin for redness post-treatment needs assessment skills to detect burns or infection, RN territory. Food reporting leverages assistants' observational role, aiding nurses in tracking radiation's impact on appetite, ensuring basic needs are flagged efficiently in a collaborative approach.
A client is receiving treatment for the diagnosis of hemophilia A. Which of the following is the most appropriate to include in the assessment of this client?
- A. Cranial nerves
- B. Appetite
- C. Joint pain and bruising
- D. Urine output
Correct Answer: C
Rationale: Hemophilia A, a factor VIII deficiency, impairs clotting joint pain and bruising from hemarthrosis and bleeds are hallmark signs, demanding assessment to gauge bleeding severity and guide factor replacement. Cranial nerves check neurologic status, irrelevant unless bleeds hit the brain. Appetite or urine output offers general insight, not hemophilia-specific. Nurses zero in on joints and skin, tracking this genetic disorder's impact, critical for managing acute episodes and preventing long-term damage in this bleeding-prone client.
Regarding infective endocarditis in an IVDU
- A. Usually presents with fever and respiratory symptoms
- B. Usually involves the mitral valve
- C. The commonest organism is staph epidermidis
- D. Negative blood cultures exclude the diagnosis
Correct Answer: A
Rationale: IVDU endocarditis fever, lung emboli from tricuspid, not mitral, Staph aureus, cultures miss some. Nurses hear this chronic right-side roar.
Which set of classification values indicates the most extensive and progressed cancer?
- A. T1 N0 M0
- B. T10 N0 M0
- C. T1 N1 M0
- D. T4 N3 M1
Correct Answer: D
Rationale: TNM staging gauges cancer extent: T (tumor size), N (node involvement), M (metastasis). T4 N3 M1 marks the worst T4 signals a large, invasive tumor, N3 extensive nodal spread, M1 distant metastases, painting a picture of widespread, advanced disease. T1 N0 M0 is small, localized, no spread early stage. T10 isn't standard (likely T1), still less severe. T1 N1 M0 has minor nodal involvement, not extensive. T4 N3 M1's combination screams progression, guiding nurses to expect aggressive care or palliation, a stark contrast to earlier stages' hopeful prognosis, critical for planning in advanced cancer.