Nokea
For prevention of tuberculosis is used
- A. specific anti-tuberculosis serum
- B. BCG
- C. DTP
- D. PPD
Correct Answer: B
Rationale: The correct answer is B: BCG. Bacille Calmette-Guérin (BCG) vaccine is used for the prevention of tuberculosis. BCG is a live attenuated strain of Mycobacterium bovis that helps the immune system recognize and fight off tuberculosis bacteria. Specific anti-tuberculosis serum (A) is not used for prevention but for treatment. DTP (C) stands for diphtheria, tetanus, and pertussis vaccine, not specific for tuberculosis prevention. PPD (D) is a tuberculin skin test used for diagnosis, not prevention. Thus, BCG is the correct choice for tuberculosis prevention.
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Which structure protects bacteria from phagocytosis?
- A. Flagella
- B. Capsule
- C. Endospore
- D. Pili
Correct Answer: B
Rationale: The correct answer is B: Capsule. Capsules are a protective layer outside the bacterial cell wall that helps bacteria evade phagocytosis by immune cells. The capsule inhibits phagocytic cells from engulfing the bacteria, making it difficult for them to be recognized and destroyed.
A: Flagella - Flagella are not involved in protecting bacteria from phagocytosis. They are responsible for bacterial movement.
C: Endospore - Endospores are dormant, resistant structures formed by some bacteria in response to harsh conditions. They do not directly protect against phagocytosis.
D: Pili - Pili are hair-like structures used for adhesion and conjugation, not for protection against phagocytosis.
A patient presented with gas gangrene. Gram-positive rods producing spores and gas were isolated from a wound sample. Identify the microorganism.
- A. Clostridium perfringens
- B. Clostridium tetani
- C. Bacillus anthracis
- D. Staphylococcus aureus
Correct Answer: A
Rationale: The correct answer is A: Clostridium perfringens. Clostridium perfringens is known to cause gas gangrene and is a Gram-positive rod that produces spores and gas in tissue infections. Clostridium tetani causes tetanus, not gas gangrene. Bacillus anthracis causes anthrax, not gas gangrene. Staphylococcus aureus is a Gram-positive cocci and does not produce spores or gas in the context of gas gangrene. Therefore, based on the characteristics of the microorganism isolated from the wound sample, Clostridium perfringens is the most likely causative agent.
A fecal sample from a patient with diarrhea revealed cysts with four nuclei. What is the most likely causative agent?
- A. Entamoeba histolytica
- B. Giardia lamblia
- C. Trichomonas vaginalis
- D. Balantidium coli
Correct Answer: A
Rationale: The correct answer is A: Entamoeba histolytica. This is because the presence of cysts with four nuclei is characteristic of Entamoeba histolytica, a protozoan parasite that causes amoebic dysentery. Entamoeba histolytica cysts contain four nuclei, distinguishing them from other pathogens. Giardia lamblia and Trichomonas vaginalis are not associated with cysts containing four nuclei. Balantidium coli is a ciliated protozoan that does not typically form cysts with multiple nuclei. In summary, the unique feature of four nuclei in the cysts points towards Entamoeba histolytica as the most likely causative agent of the diarrhea in this patient.
A patient with a sore throat and fever had a throat smear stained with Gram's method, revealing Gram-positive cocci in chains. What is the most likely causative agent?
- A. Streptococcus pyogenes
- B. Staphylococcus aureus
- C. Neisseria gonorrhoeae
- D. Enterococcus faecalis
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pyogenes. This bacterium is known to cause sore throat and fever, commonly referred to as strep throat. Gram's stain showing Gram-positive cocci in chains is characteristic of Streptococcus species. Streptococcus pyogenes is a beta-hemolytic bacterium that forms chains and is a common cause of bacterial pharyngitis. Staphylococcus aureus (B) is a Gram-positive cocci that forms clusters, not chains. Neisseria gonorrhoeae (C) is a Gram-negative diplococcus and is not associated with sore throat. Enterococcus faecalis (D) is a Gram-positive cocci that can cause infections but is not typically associated with sore throat.
While studying the pneumonic infection in 1928 the English doctor Frederick Griffith discovered:
- A. Translation
- B. Transformation
- C. Transcription
- D. Conjugation
Correct Answer: B
Rationale: The correct answer is B: Transformation. Frederick Griffith discovered bacterial transformation, where genetic material can be transferred between bacteria. He observed this phenomenon while studying pneumonia-causing bacteria in 1928. Transformation is the process by which bacteria take up external DNA and incorporate it into their own genome. This discovery was crucial in understanding how genetic information can be transferred between organisms.
Rationale for other choices:
A: Translation - This term refers to the process of protein synthesis from mRNA, not relevant to Griffith's discovery.
C: Transcription - This term refers to the process of synthesizing RNA from DNA, not related to Griffith's discovery.
D: Conjugation - This term refers to the direct transfer of genetic material between bacterial cells through cell-to-cell contact, which is different from the phenomenon Griffith observed.